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Toxicity of myristic acid analogs toward African trypanosomes.

New drugs are needed for treatment of diseases caused by African trypanosomes. One possible target for chemotherapy is the biosynthesis of the glycosyl phosphatidyl-inositol (GPI) of this parasite's variant surface glycoprotein (VSG). Unlike mammalian GPIs, the diacylglycerol moiety of the VSG...

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Detalhes bibliográficos
Main Authors: Doering, T L, Lu, T, Werbovetz, K A, Gokel, G W, Hart, G W, Gordon, J I, Englund, P T
Formato: Artigo
Idioma:en
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44891/
https://ncbi.nlm.nih.gov/pubmed/7937882
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