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Serum-induced membrane depolarization in quiescent fibroblasts: activation of a chloride conductance through the G protein-coupled LPA receptor.

Serum stimulation of quiescent fibroblasts leads to a dramatic depolarization of the plasma membrane; however, the identity of the active serum factor(s) and the underlying mechanism are unknown. We find that this serum activity is attributable to albumin-bound lysophosphatidic acid (LPA) acting on...

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Detalhes bibliográficos
Main Authors: Postma, F R, Jalink, K, Hengeveld, T, Bot, A G, Alblas, J, de Jonge, H R, Moolenaar, W H
Formato: Artigo
Idioma:English
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC449918/
https://ncbi.nlm.nih.gov/pubmed/8598207
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