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Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE(2) in colorectal cancer
BACKGROUND: Misregulation of the PTGS (prostaglandin endoperoxide synthase, also known as cyclooxygenase or COX) pathway may lead to the accumulation of pro-inflammatory signals, which constitutes a hallmark of cancer. To get insight into the role of this signaling pathway in colorectal cancer (CRC)...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
BioMed Central
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512023/ https://ncbi.nlm.nih.gov/pubmed/26207152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0110-4 |
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