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Synergistic anti-human immunodeficiency virus type 1 effect of hydroxamate compounds with 2',3'-dideoxyinosine in infected resting human lymphocytes.

The cellular models generally used in the in vitro evaluation of anti-human immunodeficiency virus compounds are dividing cells. A model constituted by resting lymphocytes may more accurately reflect a drug's future efficacy in humans, since viral DNA synthesis is known to take place in quiesce...

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Detalhes bibliográficos
Main Authors: Malley, S D, Grange, J M, Hamedi-Sangsari, F, Vila, J R
Formato: Artigo
Idioma:en
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45157/
https://ncbi.nlm.nih.gov/pubmed/7972000
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