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Structural insights into interactions between ubiquitin specific protease 5 and its polyubiquitin substrates by mass spectrometry and ion mobility spectrometry

Nanoelectrospray ionization-mass spectrometry and ion mobility-mass spectrometry have been used to study the interactions of the large, multidomain, and conformationally flexible deubiquitinating enzyme ubiquitin specific protease 5 (USP5) with mono- and poly-ubiquitin (Ub) substrates. Employing a C...

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Formato: Artigo
Idioma:en
Publicado em: John Wiley & Sons, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534176/
https://ncbi.nlm.nih.gov/pubmed/25970461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2692
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