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Phosphatase and Tensin Homologue: Novel Regulation by Developmental Signaling
Phosphatase and tensin homologue (PTEN) is a critical cell endogenous inhibitor of phosphoinositide signaling in mammalian cells. PTEN dephosphorylates phosphoinositide trisphosphate (PIP(3)), and by so doing PTEN has the function of negative regulation of Akt, thereby inhibiting this key intracellu...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539077/ https://ncbi.nlm.nih.gov/pubmed/26339505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/282567 |
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