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Murine Antibody Responses to Cleaved Soluble HIV-1 Envelope Trimers Are Highly Restricted in Specificity

Generating neutralizing antibodies (nAbs) is a major goal of many current HIV-1 vaccine efforts. To be of practical value, these nAbs must be both potent and cross-reactive in order to be capable of preventing the transmission of the highly diverse and generally neutralization resistant (Tier-2) HIV...

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Bibliografiske detaljer
Format: Artigo
Sprog:en
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580201/
https://ncbi.nlm.nih.gov/pubmed/26246566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01653-15
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