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Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages
Pyrazinamide (PZA) is active against major Mycobacterium tuberculosis species (M. tuberculosis, M. africanum, and M. microti) but not against M. bovis and M. avium. The latter two are mycobacterial species involved in human and cattle tuberculosis and in HIV coinfections, respectively. PZA is a firs...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Microbiology
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4649235/ https://ncbi.nlm.nih.gov/pubmed/26438493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00936-15 |
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