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Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases
The KDM5/JARID1 family of Fe(II)- and α-ketoglutarate-dependent demethylases remove methyl groups from tri- and dimethylated lysine 4 of histone H3. Accumulating evidence from primary tumors and model systems supports a role for KDM5A (JARID1A/RBP2) and KDM5B (JARID1B/PLU1) as oncogenic drivers. The...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742734/ https://ncbi.nlm.nih.gov/pubmed/26645689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698449 |
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