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Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes
Acetaminophen (APAP) is a readily available over-the-counter drug and is one of the most commonly used analgesics/antipyretics worldwide. Large interindividual variation in susceptibility toward APAP-induced liver failure has been reported. However, the exact underlying factors causing this variabil...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
Springer Berlin Heidelberg
2015
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830893/ https://ncbi.nlm.nih.gov/pubmed/26104854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-015-1545-2 |
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