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A clinically relevant pharmacokinetic interaction between cyclosporine and imatinib
PURPOSE: Cyclosporine A (CsA) and imatinib are both CYP3A4 and P-glycoprotein substrates. Concomitant use after hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML) or Philadelphia chromosome-positive (Ph+) acute lymphatic leukemia (ALL) may therefore result in a pharmac...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865545/ https://ncbi.nlm.nih.gov/pubmed/26965514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-016-2038-9 |
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