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cDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase.
The antiinflammatory glucocorticoids are potent inhibitors of cyclooxygenase, a key regulator of prostaglandin synthesis; yet, the mechanism(s) by which this occurs is not fully understood. We have cloned a 4.1-kilobase (kb) cDNA, distinct from the previously cloned cyclooxygenase (2.8 kb), that con...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado em: |
1992
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC49193/ https://ncbi.nlm.nih.gov/pubmed/1594589 |
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