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Inhibition of human immunodeficiency virus activity by phosphorodithioate oligodeoxycytidine.

Phosphorothioate oligodeoxynucleotides exert a sequence-independent cytoprotective effect against human immunodeficiency virus type 1 (HIV-1). We now report that phosphorodithioate-containing oligodeoxycytidines are very potent inhibitors of HIV-1 reverse transcriptase in vitro, as they exhibit an i...

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Detalhes bibliográficos
Main Authors: Marshall, W S, Beaton, G, Stein, C A, Matsukura, M, Caruthers, M H
Formato: Artigo
Idioma:en
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49481/
https://ncbi.nlm.nih.gov/pubmed/1378623
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