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BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans
Human blood cell counts are tightly maintained within narrow physiologic ranges, largely controlled by cytokine-integrated signaling and transcriptional circuits that regulate multilineage hematopoietic specification. Known genetic loci influencing blood cell production account for <10% of platel...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society of Hematology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974201/ https://ncbi.nlm.nih.gov/pubmed/27207795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-696997 |
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