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Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy
Glomerular apoptosis may contribute to diabetic nephropathy (dNP), but the pathophysiologic relevance of this process remains obscure. Here, we administered two partially disjunct polycaspase inhibitors in 8-week-old diabetic (db/db) mice: M-920 (inhibiting caspase-1, -3, -4, -5, -6, -7, and -8) and...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society of Nephrology
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978051/ https://ncbi.nlm.nih.gov/pubmed/26832955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060676 |
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