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Functional Divergence between Co-chaperones of Hsc70()
The ATPase cycle of the chaperone Hsc70 is regulated by co-chaperones; Hsp40/DnaJ-related proteins stimulate ATP hydrolysis by Hsc70 and can bind unfolded polypeptides themselves. Conversely, various nucleotide exchange factors (NEFs) stimulate ADP-ATP exchange by Hsc70. We analyzed the purified Hsp...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026489/ https://ncbi.nlm.nih.gov/pubmed/18684711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803923200 |
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