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Human fusion proteins between interleukin 2 and IgM heavy chain are cytotoxic for cells expressing the interleukin 2 receptor.

We have constructed a hybrid cDNA coding for a fusion protein between human interleukin 2 and a truncated heavy chain from human immunoglobulin M. The protein encoded by this cDNA contains the entire interleukin 2 sequence including its signal peptide, fused at its C terminus to domains 2 to 4 of th...

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Detalhes bibliográficos
Main Authors: Vié, H, Gauthier, T, Breathnach, R, Bonneville, M, Godard, A, Dietrich, J, Karam, G, Gesnel, M C, Peyrat, M A, Jacques, Y
Formato: Artigo
Idioma:en
Publicado em: 1992
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50545/
https://ncbi.nlm.nih.gov/pubmed/1454817
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