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Artificial Intelligence vs. Statistical Modeling and Optimization of Continuous Bead Milling Process for Bacterial Cell Lysis
For a commercially viable recombinant intracellular protein production process, efficient cell lysis and protein release is a major bottleneck. The recovery of recombinant protein, cholesterol oxidase (COD) was studied in a continuous bead milling process. A full factorial response surface methodolo...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
Frontiers Media S.A.
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118707/ https://ncbi.nlm.nih.gov/pubmed/27920762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01852 |
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