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Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium
Cytochrome P450 monooxygenases (P450s) are attractive enzymes for the pharmaceutical industry, in particular, for applications in steroidal drug synthesis. Here, we report a comprehensive functional and structural characterization of CYP109E1, a novel steroid‐converting cytochrome P450 enzyme identi...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5132081/ https://ncbi.nlm.nih.gov/pubmed/27686671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13911 |
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