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Transposon Express, a software application to report the identity of insertions obtained by comprehensive transposon mutagenesis of sequenced genomes: analysis of the preference for in vitro Tn5 transposition into GC-rich DNA

Comprehensive mutant libraries can be readily constructed by transposon mutagenesis. To systematically mutagenise the genome of the Gram-positive bacterium Streptomyces coelicolor A3(2), we have employed high-throughput shuttle transposon mutagenesis of a cosmid library prepared in Escherichia coli....

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Detalhes bibliográficos
Main Authors: Herron, Paul R., Hughes, Gareth, Chandra, Govind, Fielding, Susan, Dyson, Paul J.
Formato: Artigo
Idioma:English
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514396/
https://ncbi.nlm.nih.gov/pubmed/15308758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh112
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