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The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions

RAS effectors specifically interact with the GTP-bound form of RAS in response to extracellular signals and link them to downstream signaling pathways. The molecular nature of effector interaction by RAS is well-studied but yet still incompletely understood in a comprehensive and systematic way. Her...

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Formato: Artigo
Idioma:en
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147862/
https://ncbi.nlm.nih.gov/pubmed/27936046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167145
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