The AraC Family Transcriptional Regulator Rv1931c Plays a Role in the Virulence of Mycobacterium tuberculosis

A Mycobacterium tuberculosis strain disrupted in the AraC homologue Rv1931c was isolated. The mutant strain exhibited reduced survival both in macrophages and in a mouse infection model, with survival being restored on complementation with the Rv1931c gene. These results suggest that Rv1931c regulat...

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Detalhes bibliográficos
Main Authors: Frota, Cristiane C., Papavinasasundaram, K. G., Davis, Elaine O., Colston, M. Joseph
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517439/
https://ncbi.nlm.nih.gov/pubmed/15322050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5483-5486.2004
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https://ncbi.nlm.nih.gov/pmc/articles/PMC517439/
https://ncbi.nlm.nih.gov/pubmed/15322050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.9.5483-5486.2004

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