Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

The Raf/MEK/extracellular signal–regulated kinase (ERK) signaling pathway regulates diverse cellular processes such as proliferation, differentiation, and apoptosis and is implicated as an important contributor to the pathogenesis of cardiac hypertrophy and heart failure. To examine the in vivo role...

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Detalhes bibliográficos
Main Authors: Yamaguchi, Osamu, Watanabe, Tetsuya, Nishida, Kazuhiko, Kashiwase, Kazunori, Higuchi, Yoshiharu, Takeda, Toshihiro, Hikoso, Shungo, Hirotani, Shinichi, Asahi, Michio, Taniike, Masayuki, Nakai, Atsuko, Tsujimoto, Ikuko, Matsumura, Yasushi, Miyazaki, Jun-ichi, Chien, Kenneth R., Matsuzawa, Atsushi, Sadamitsu, Chiharu, Ichijo, Hidenori, Baccarini, Manuela, Hori, Masatsugu, Otsu, Kinya
Formato: Artigo
Idioma:English
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC518660/
https://ncbi.nlm.nih.gov/pubmed/15467832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420317
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https://ncbi.nlm.nih.gov/pmc/articles/PMC518660/
https://ncbi.nlm.nih.gov/pubmed/15467832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420317

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