Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

The Raf/MEK/extracellular signal–regulated kinase (ERK) signaling pathway regulates diverse cellular processes such as proliferation, differentiation, and apoptosis and is implicated as an important contributor to the pathogenesis of cardiac hypertrophy and heart failure. To examine the in vivo role...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yamaguchi, Osamu, Watanabe, Tetsuya, Nishida, Kazuhiko, Kashiwase, Kazunori, Higuchi, Yoshiharu, Takeda, Toshihiro, Hikoso, Shungo, Hirotani, Shinichi, Asahi, Michio, Taniike, Masayuki, Nakai, Atsuko, Tsujimoto, Ikuko, Matsumura, Yasushi, Miyazaki, Jun-ichi, Chien, Kenneth R., Matsuzawa, Atsushi, Sadamitsu, Chiharu, Ichijo, Hidenori, Baccarini, Manuela, Hori, Masatsugu, Otsu, Kinya
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: American Society for Clinical Investigation 2004
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC518660/
https://ncbi.nlm.nih.gov/pubmed/15467832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420317
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