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Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles.

The alpha i2 subunit of the inhibitory heterotrimeric guanine nucleotide-binding proteins is highly conserved in mammals and is expressed in all cell types, but its exact function is not yet defined. We have investigated the role of this protein by producing embryonic stem (ES) cells lacking a funct...

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Detalhes bibliográficos
Main Authors:	Mortensen, R M, Zubiaur, M, Neer, E J, Seidman, J G, Saito, K, Noji, M, Ohmori, S, Imai, Y, Murakoshi, I, Zhurkin, V B, Ulyanov, N B, Gorin, A A, Jernigan, R L, Jung, J U, Trimble, J J, King, N W, Biesinger, B, Fleckenstein, B W, Desrosiers, R C, Ashkenazi, A, Smith, D H, Marsters, S A, Riddle, L, Gregory, T J, Ho, D D, Capon, D J, Miraglia, L, Seiwert, S, Igel, A H, Ares, M, Born, R T, Tootell, R B, Hillman, D, Chen, S, Aung, T T, Cherksey, B, Sugimori, M, Llinás, R R, Osawa, Y, Korzekwa, K, Ray, A, LaForge, K S, Sehgal, P B, Giovanelli, J, Campos, K L, Kaufman, S, Schönthal, A, Sugarman, J, Brown, J H, Hanley, M R, Feramisco, J R, Wang, K, McCarter, R, Wright, J, Beverly, J, Ramirez-Mitchell, R, Berg, M M, Sternberg, D W, Hempstead, B L, Chao, M V, McBride, K, Rhee, S G, Jaken, S, Geyer, P K, Chien, A J, Corces, V G, Green, M M, Tiercy, J M, Morel, C, Freidel, A C, Zwahlen, F, Gebuhrer, L, Bétuel, H, Jeannet, M, Mach, B, Shafferman, A, Jahrling, P B, Benveniste, R E, Lewis, M G, Phipps, T J, Eden-McCutchan, F, Sadoff, J, Eddy, G A, Burke, D S, Bhat, S, Spitalnik, S L, Gonzalez-Scarano, F, Silberberg, D H, Heidelberger, R, Matthews, G, Ghadge, G D, Swaminathan, S, Katze, M G, Thimmapaya, B, Unge, T, Solomin, L, Mellini, M, Derse, D, Felber, B K, Pavlakis, G N, Nakamura, S, Rodbell, M, Verma, R, Patapoutian, A, Gordon, C B, Campbell, J L, Drake, J W, Knowles, B A, Hawley, R S, Cruz, A, Coburn, C M, Beverley, S M, Devi, S J, Robbins, J B, Schneerson, R, Hamilton, J A, Piccoli, D S, Leizer, T, Butler, D M, Croatto, M, Royston, A K, Hershfield, M S, Chaffee, S, Koro-Johnson, L, Mary, A, Smith, A A, Short, S A, Keller, J R, Jacobsen, S E, Sill, K T, Ellingsworth, L R, Ruscetti, F W, Welcher, A A, Suter, U, De Leon, M, Snipes, G J, Shooter, E M, Etingin, O R, Silverstein, R L, Hajjar, D P, Donson, J, Kearney, C M, Hilf, M E, Dawson, W O, Ffrench-Constant, R H, Mortlock, D P, Shaffer, C D, MacIntyre, R J, Roush, R T, Delaney, S J, Hayward, D C, Barleben, F, Fischbach, K F, Miklos, G L, Desquenne-Clark, L, Esch, T R, Otvos, L, Heber-Katz, E, Philippe, J, Russell, J K, Pontzer, C H, Johnson, H M, Lee, K S, Frank, S, Vanderklish, P, Arai, A, Lynch, G, Ferre, S, von Euler, G, Johansson, B, Fredholm, B B, Fuxe, K, Lombroso, P J, Murdoch, G, Lerner, M, Kowall, N W, Beal, M F, Busciglio, J, Duffy, L K, Yankner, B A, Corfas, G, Dudai, Y, Gibbs, A, Mousseau, T A, Crowe, J H, Higley, J D, Hasert, M F, Suomi, S J, Linnoila, M, Skriver, K, Olsen, F L, Rogers, J C, Mundy, J, Bibi, E, Verner, G, Chang, C Y, Kaback, H R, Holland, P M, Abramson, R D, Watson, R, Gelfand, D H
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC52228/ https://ncbi.nlm.nih.gov/pubmed/1908087 https://ncbi.nlm.nih.gov/pmc/articles/PMC52229/ https://ncbi.nlm.nih.gov/pubmed/1714583 https://ncbi.nlm.nih.gov/pmc/articles/PMC52230/ https://ncbi.nlm.nih.gov/pubmed/1871119 https://ncbi.nlm.nih.gov/pmc/articles/PMC52231/ https://ncbi.nlm.nih.gov/pubmed/1651491 https://ncbi.nlm.nih.gov/pmc/articles/PMC52232/ https://ncbi.nlm.nih.gov/pubmed/1871120 https://ncbi.nlm.nih.gov/pmc/articles/PMC52233/ https://ncbi.nlm.nih.gov/pubmed/1871121 https://ncbi.nlm.nih.gov/pmc/articles/PMC52234/ https://ncbi.nlm.nih.gov/pubmed/1651492 https://ncbi.nlm.nih.gov/pmc/articles/PMC52235/ https://ncbi.nlm.nih.gov/pubmed/1871122 https://ncbi.nlm.nih.gov/pmc/articles/PMC52236/ https://ncbi.nlm.nih.gov/pubmed/1651493 https://ncbi.nlm.nih.gov/pmc/articles/PMC52237/ https://ncbi.nlm.nih.gov/pubmed/1871123 https://ncbi.nlm.nih.gov/pmc/articles/PMC52238/ https://ncbi.nlm.nih.gov/pubmed/1871124 https://ncbi.nlm.nih.gov/pmc/articles/PMC52239/ https://ncbi.nlm.nih.gov/pubmed/1714584 https://ncbi.nlm.nih.gov/pmc/articles/PMC52240/ https://ncbi.nlm.nih.gov/pubmed/1714585 https://ncbi.nlm.nih.gov/pmc/articles/PMC52241/ https://ncbi.nlm.nih.gov/pubmed/1714586 https://ncbi.nlm.nih.gov/pmc/articles/PMC52242/ https://ncbi.nlm.nih.gov/pubmed/1714587 https://ncbi.nlm.nih.gov/pmc/articles/PMC52243/ https://ncbi.nlm.nih.gov/pubmed/1651494 https://ncbi.nlm.nih.gov/pmc/articles/PMC52244/ https://ncbi.nlm.nih.gov/pubmed/1714588 https://ncbi.nlm.nih.gov/pmc/articles/PMC52245/ https://ncbi.nlm.nih.gov/pubmed/1908088 https://ncbi.nlm.nih.gov/pmc/articles/PMC52246/ https://ncbi.nlm.nih.gov/pubmed/1871125 https://ncbi.nlm.nih.gov/pmc/articles/PMC52247/ https://ncbi.nlm.nih.gov/pubmed/1871126 https://ncbi.nlm.nih.gov/pmc/articles/PMC52248/ https://ncbi.nlm.nih.gov/pubmed/1651495 https://ncbi.nlm.nih.gov/pmc/articles/PMC52249/ https://ncbi.nlm.nih.gov/pubmed/1714589 https://ncbi.nlm.nih.gov/pmc/articles/PMC52250/ https://ncbi.nlm.nih.gov/pubmed/1871127 https://ncbi.nlm.nih.gov/pmc/articles/PMC52251/ https://ncbi.nlm.nih.gov/pubmed/1908089 https://ncbi.nlm.nih.gov/pmc/articles/PMC52252/ https://ncbi.nlm.nih.gov/pubmed/1871128 https://ncbi.nlm.nih.gov/pmc/articles/PMC52253/ https://ncbi.nlm.nih.gov/pubmed/1831267 https://ncbi.nlm.nih.gov/pmc/articles/PMC52254/ https://ncbi.nlm.nih.gov/pubmed/1908090 https://ncbi.nlm.nih.gov/pmc/articles/PMC52255/ https://ncbi.nlm.nih.gov/pubmed/1651496 https://ncbi.nlm.nih.gov/pmc/articles/PMC52256/ https://ncbi.nlm.nih.gov/pubmed/1908091 https://ncbi.nlm.nih.gov/pmc/articles/PMC52257/ https://ncbi.nlm.nih.gov/pubmed/1908092 https://ncbi.nlm.nih.gov/pmc/articles/PMC52258/ https://ncbi.nlm.nih.gov/pubmed/1714590 https://ncbi.nlm.nih.gov/pmc/articles/PMC52259/ https://ncbi.nlm.nih.gov/pubmed/1831268 https://ncbi.nlm.nih.gov/pmc/articles/PMC52260/ https://ncbi.nlm.nih.gov/pubmed/1714591 https://ncbi.nlm.nih.gov/pmc/articles/PMC52261/ https://ncbi.nlm.nih.gov/pubmed/1714592 https://ncbi.nlm.nih.gov/pmc/articles/PMC52262/ https://ncbi.nlm.nih.gov/pubmed/1651497 https://ncbi.nlm.nih.gov/pmc/articles/PMC52263/ https://ncbi.nlm.nih.gov/pubmed/1651498 https://ncbi.nlm.nih.gov/pmc/articles/PMC52264/ https://ncbi.nlm.nih.gov/pubmed/1714593 https://ncbi.nlm.nih.gov/pmc/articles/PMC52265/ https://ncbi.nlm.nih.gov/pubmed/1714594 https://ncbi.nlm.nih.gov/pmc/articles/PMC52266/ https://ncbi.nlm.nih.gov/pubmed/1651499 https://ncbi.nlm.nih.gov/pmc/articles/PMC52267/ https://ncbi.nlm.nih.gov/pubmed/1871129 https://ncbi.nlm.nih.gov/pmc/articles/PMC52268/ https://ncbi.nlm.nih.gov/pubmed/1871130 https://ncbi.nlm.nih.gov/pmc/articles/PMC52269/ https://ncbi.nlm.nih.gov/pubmed/1678519 https://ncbi.nlm.nih.gov/pmc/articles/PMC52270/ https://ncbi.nlm.nih.gov/pubmed/1714595 https://ncbi.nlm.nih.gov/pmc/articles/PMC52271/ https://ncbi.nlm.nih.gov/pubmed/1714596 https://ncbi.nlm.nih.gov/pmc/articles/PMC52272/ https://ncbi.nlm.nih.gov/pubmed/1714597 https://ncbi.nlm.nih.gov/pmc/articles/PMC52273/ https://ncbi.nlm.nih.gov/pubmed/11607207 https://ncbi.nlm.nih.gov/pmc/articles/PMC52274/ https://ncbi.nlm.nih.gov/pubmed/1871131 https://ncbi.nlm.nih.gov/pmc/articles/PMC52275/ https://ncbi.nlm.nih.gov/pubmed/1831269 https://ncbi.nlm.nih.gov/pmc/articles/PMC52276/ https://ncbi.nlm.nih.gov/pubmed/1871132 https://ncbi.nlm.nih.gov/pmc/articles/PMC52277/ https://ncbi.nlm.nih.gov/pubmed/1871133
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