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Phage display of ricin B chain and its single binding domains: system for screening galactose-binding mutants.
We demonstrate that the B chain of ricin toxin preserves its lectin activity when expressed as a fusion protein on the surface of fd phage. Moreover, B chain, which folds into two topologically similar globular domains, can be dissected into amino-terminal and carboxyl-terminal domains to form singl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
1992
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC525569/ https://ncbi.nlm.nih.gov/pubmed/1373889 |
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