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Mucosal Antibodies to the C Terminus of Toxin A Prevent Colonization of Clostridium difficile
Mucosal immunity is considered important for protection against Clostridium difficile infection (CDI). We show that in hamsters immunized with Bacillus subtilis spores expressing a carboxy-terminal segment (TcdA(26–39)) of C. difficile toxin A, no colonization occurs in protected animals when challe...
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| Formato: | Artigo |
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| Idioma: | en |
| Publicado em: |
American Society for Microbiology
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5364299/ https://ncbi.nlm.nih.gov/pubmed/28167669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01060-16 |
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