Diabetes Acceleration or Prevention by a Coxsackievirus B4 Infection: Critical Requirements for both Interleukin-4 and Gamma Interferon

Type 1 diabetes acceleration in nonobese diabetic (NOD) mice through coxsackievirus B4 (CVB4) infection requires a preexisting critical mass of autoreactive T cells in pancreatic islets, and in the absence of this insulitic threshold, CVB4 infection leads to long-term disease protection. To understa...

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Detalhes bibliográficos
Main Authors: Serreze, David V., Wasserfall, Clive, Ottendorfer, Eric W., Stalvey, Michael, Pierce, Melissa A., Gauntt, Charles, O'Donnell, Brian, Flanagan, James B., Campbell-Thompson, Martha, Ellis, Tamir M., Atkinson, Mark A.
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538592/
https://ncbi.nlm.nih.gov/pubmed/15613333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1045-1052.2005
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https://ncbi.nlm.nih.gov/pmc/articles/PMC538592/
https://ncbi.nlm.nih.gov/pubmed/15613333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1045-1052.2005

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