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The spatial distribution of exposed nuclear DNA in normal, cancer, and reverse-transformed cells.

The malignant CHO-K1 cell is reverse-transformed by cAMP, regaining the phenotype of a normal fibroblast. During this reaction, much of its DNA re-acquires sensitivity to hydrolysis by DNase I in a way characteristic of the normal fibroblast. Exposed DNA forms a rim about the nucleus in both the nor...

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Detalhes bibliográficos
Main Authors:	Krystosek, A, Puck, T T, Ala-Kokko, L, Baldwin, C T, Moskowitz, R W, Prockop, D J, Wahlberg, J, Lundeberg, J, Hultman, T, Uhlén, M, Daar, E S, Li, X L, Moudgil, T, Ho, D D, Georgi, A, Mottola-Hartshorn, C, Warner, A, Fields, B, Chen, L B, Okamoto, Y, Minamoto, S, Shimizu, K, Mogami, H, Taniguchi, T, Costa, R H, Van Dyke, T A, Yan, C, Kuo, F, Darnell, J E, Schwartz, L M, Kosz, L, Kay, B K, Milich, D R, Jones, J E, Hughes, J L, Price, J, Raney, A K, McLachlan, A, Wieties, K, Hammer, R E, Jones-Youngblood, S, Forman, J, Marshall, B, Petrowski, D, Levy, S B, Lam, W L, Cohen, A, Tsouluhas, D, Doolittle, W F, Kawaguchi, T, Kitajima, S, Niho, Y, Oda, T, Germino, J, Weissman, S M, Yasukochi, Y, Good, D J, Polverini, P J, Rastinejad, F, Le Beau, M M, Lemons, R S, Frazier, W A, Bouck, N P, Kranz, J E, Holm, C, Lichter, P, Ledbetter, S A, Ledbetter, D H, Ward, D C, Cherif, D, Julier, C, Delattre, O, Derré, J, Lathrop, G M, Berger, R, DesJarlais, R L, Seibel, G L, Kuntz, I D, Furth, P S, Alvarez, J C, Ortiz de Montellano, P R, DeCamp, D L, Babé, L M, Craik, C S, Kelliher, M A, McLaughlin, J, Witte, O N, Rosenberg, N, Roberts, V A, Iverson, B L, Iverson, S A, Benkovic, S J, Lerner, R A, Getzoff, E D, Tainer, J A, Evnin, L B, Vásquez, J R, Syväoja, J, Suomensaari, S, Nishida, C, Goldsmith, J S, Chui, G S, Jain, S, Linn, S, Exposito, J Y, Garrone, R, Larsen, R D, Ernst, L K, Nair, R P, Lowe, J B, Barnes, D E, Johnston, L H, Kodama, K, Tomkinson, A E, Lasko, D D, Lindahl, T, Shimoda, N, Toyoda-Yamamoto, A, Nagamine, J, Usami, S, Katayama, M, Sakagami, Y, Machida, Y, Biswas, E E, Stefanec, M J, Biswas, S B, Webster, G D, Sanderson, M R, Skelly, J V, Neidle, S, Swann, P F, Li, B F, Tickle, I J, Fridman, R, Giaccone, G, Kanemoto, T, Martin, G R, Gazdar, A F, Mulshine, J L, Li, W H, Gouy, M, Sharp, P M, O'hUigin, C, Yang, Y W, Cangelosi, G A, Ankenbauer, R G, Nester, E W, Willard-Gallo, K E, Van de Keere, F, Kettmann, R, Zador, A, Koch, C, Brown, T H, Monsma, F J, Mahan, L C, McVittie, L D, Gerfen, C R, Sibley, D R, Hughes, J, Boden, P, Costall, B, Domeney, A, Kelly, E, Horwell, D C, Hunter, J C, Pinnock, R D, Woodruff, G N, Hamada, N, Engelman, R W, Tomita, Y, Chen, R F, Iwai, H, Good, R A, Day, N K, Roussel, M F, Shurtleff, S A, Downing, J R, Sherr, C J, Elroy-Stein, O, Moss, B, Li, H M, Theg, S M, Bauerle, C M, Keegstra, K, Scarlato, V, Prugnola, A, Aricó, B, Rappuoli, R, Dubravec, D B, Spriggs, D R, Mannick, J A, Rodrick, M L, Banks, W A, Schally, A V, Barrera, C M, Fasold, M B, Durham, D A, Csernus, V J, Groot, K, Kastin, A J, Reuben, M A, Lasater, L S, Sachs, G, Blaseio, U, Pfeifer, F, England, J D, Gamboni, F, Levinson, S R, Finger, T E, Gafvelin, G, Jörnvall, H, Mutt, V, Parad, R B, Kramer, J, Strunk, R C, Rosen, F S, Davis, A E, Tsuda, H, Zhang, W D, Shimosato, Y, Yokota, J, Terada, M, Sugimura, T, Miyamura, T, Hirohashi, S, Gross, L, Dreyfuss, Y, Bhargava, A K, Woitach, J T, Davidson, E A, Bhavanandan, V P
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC54576/ https://ncbi.nlm.nih.gov/pubmed/1697684 https://ncbi.nlm.nih.gov/pmc/articles/PMC54577/ https://ncbi.nlm.nih.gov/pubmed/1975693 https://ncbi.nlm.nih.gov/pmc/articles/PMC54578/ https://ncbi.nlm.nih.gov/pubmed/2118652 https://ncbi.nlm.nih.gov/pmc/articles/PMC54579/ https://ncbi.nlm.nih.gov/pubmed/2395859 https://ncbi.nlm.nih.gov/pmc/articles/PMC54580/ https://ncbi.nlm.nih.gov/pubmed/2118653 https://ncbi.nlm.nih.gov/pmc/articles/PMC54581/ https://ncbi.nlm.nih.gov/pubmed/2395860 https://ncbi.nlm.nih.gov/pmc/articles/PMC54582/ https://ncbi.nlm.nih.gov/pubmed/2395861 https://ncbi.nlm.nih.gov/pmc/articles/PMC54583/ https://ncbi.nlm.nih.gov/pubmed/2395862 https://ncbi.nlm.nih.gov/pmc/articles/PMC54584/ https://ncbi.nlm.nih.gov/pubmed/2395863 https://ncbi.nlm.nih.gov/pmc/articles/PMC54585/ https://ncbi.nlm.nih.gov/pubmed/2395864 https://ncbi.nlm.nih.gov/pmc/articles/PMC54586/ https://ncbi.nlm.nih.gov/pubmed/2204058 https://ncbi.nlm.nih.gov/pmc/articles/PMC54587/ https://ncbi.nlm.nih.gov/pubmed/2118654 https://ncbi.nlm.nih.gov/pmc/articles/PMC54588/ https://ncbi.nlm.nih.gov/pubmed/2395865 https://ncbi.nlm.nih.gov/pmc/articles/PMC54589/ https://ncbi.nlm.nih.gov/pubmed/1697685 https://ncbi.nlm.nih.gov/pmc/articles/PMC54590/ https://ncbi.nlm.nih.gov/pubmed/2204059 https://ncbi.nlm.nih.gov/pmc/articles/PMC54591/ https://ncbi.nlm.nih.gov/pubmed/2395866 https://ncbi.nlm.nih.gov/pmc/articles/PMC54592/ https://ncbi.nlm.nih.gov/pubmed/2395867 https://ncbi.nlm.nih.gov/pmc/articles/PMC54593/ https://ncbi.nlm.nih.gov/pubmed/2204060 https://ncbi.nlm.nih.gov/pmc/articles/PMC54594/ https://ncbi.nlm.nih.gov/pubmed/2204061 https://ncbi.nlm.nih.gov/pmc/articles/PMC54595/ https://ncbi.nlm.nih.gov/pubmed/2395868 https://ncbi.nlm.nih.gov/pmc/articles/PMC54596/ https://ncbi.nlm.nih.gov/pubmed/2204062 https://ncbi.nlm.nih.gov/pmc/articles/PMC54597/ https://ncbi.nlm.nih.gov/pubmed/1975694 https://ncbi.nlm.nih.gov/pmc/articles/PMC54598/ https://ncbi.nlm.nih.gov/pubmed/2395869 https://ncbi.nlm.nih.gov/pmc/articles/PMC54599/ https://ncbi.nlm.nih.gov/pubmed/2118655 https://ncbi.nlm.nih.gov/pmc/articles/PMC54600/ https://ncbi.nlm.nih.gov/pubmed/2204063 https://ncbi.nlm.nih.gov/pmc/articles/PMC54601/ https://ncbi.nlm.nih.gov/pubmed/11607097 https://ncbi.nlm.nih.gov/pmc/articles/PMC54602/ https://ncbi.nlm.nih.gov/pubmed/1697686 https://ncbi.nlm.nih.gov/pmc/articles/PMC54603/ https://ncbi.nlm.nih.gov/pubmed/2395870 https://ncbi.nlm.nih.gov/pmc/articles/PMC54604/ https://ncbi.nlm.nih.gov/pubmed/2168554 https://ncbi.nlm.nih.gov/pmc/articles/PMC54605/ https://ncbi.nlm.nih.gov/pubmed/2395871 https://ncbi.nlm.nih.gov/pmc/articles/PMC54606/ https://ncbi.nlm.nih.gov/pubmed/2118656 https://ncbi.nlm.nih.gov/pmc/articles/PMC54607/ https://ncbi.nlm.nih.gov/pubmed/2144349 https://ncbi.nlm.nih.gov/pmc/articles/PMC54608/ https://ncbi.nlm.nih.gov/pubmed/2168555 https://ncbi.nlm.nih.gov/pmc/articles/PMC54609/ https://ncbi.nlm.nih.gov/pubmed/2168556 https://ncbi.nlm.nih.gov/pmc/articles/PMC54610/ https://ncbi.nlm.nih.gov/pubmed/1975695 https://ncbi.nlm.nih.gov/pmc/articles/PMC54611/ https://ncbi.nlm.nih.gov/pubmed/1975696 https://ncbi.nlm.nih.gov/pmc/articles/PMC54612/ https://ncbi.nlm.nih.gov/pubmed/2168557 https://ncbi.nlm.nih.gov/pmc/articles/PMC54613/ https://ncbi.nlm.nih.gov/pubmed/2204064 https://ncbi.nlm.nih.gov/pmc/articles/PMC54614/ https://ncbi.nlm.nih.gov/pubmed/11607098 https://ncbi.nlm.nih.gov/pmc/articles/PMC54615/ https://ncbi.nlm.nih.gov/pubmed/1697687 https://ncbi.nlm.nih.gov/pmc/articles/PMC54616/ https://ncbi.nlm.nih.gov/pubmed/1697688 https://ncbi.nlm.nih.gov/pmc/articles/PMC54617/ https://ncbi.nlm.nih.gov/pubmed/1975697 https://ncbi.nlm.nih.gov/pmc/articles/PMC54618/ https://ncbi.nlm.nih.gov/pubmed/2168558 https://ncbi.nlm.nih.gov/pmc/articles/PMC54619/ https://ncbi.nlm.nih.gov/pubmed/11607099 https://ncbi.nlm.nih.gov/pmc/articles/PMC54620/ https://ncbi.nlm.nih.gov/pubmed/2168559 https://ncbi.nlm.nih.gov/pmc/articles/PMC54621/ https://ncbi.nlm.nih.gov/pubmed/2395872 https://ncbi.nlm.nih.gov/pmc/articles/PMC54622/ https://ncbi.nlm.nih.gov/pubmed/2118657 https://ncbi.nlm.nih.gov/pmc/articles/PMC54623/ https://ncbi.nlm.nih.gov/pubmed/2168560 https://ncbi.nlm.nih.gov/pmc/articles/PMC54624/ https://ncbi.nlm.nih.gov/pubmed/2395873 https://ncbi.nlm.nih.gov/pmc/articles/PMC54625/ https://ncbi.nlm.nih.gov/pubmed/2204065
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The spatial distribution of exposed nuclear DNA in normal, cancer, and reverse-transformed cells.

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