SIRT1 Regulates HIV Transcription via Tat Deacetylation

The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is deacetylated by human sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide-dependent class III protein deacetylase...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pagans, Sara, Pedal, Angelika, North, Brian J, Kaehlcke, Katrin, Marshall, Brett L, Dorr, Alexander, Hetzer-Egger, Claudia, Henklein, Peter, Frye, Roy, McBurney, Michael W, Hruby, Henning, Jung, Manfred, Verdin, Eric, Ott, Melanie
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546329/
https://ncbi.nlm.nih.gov/pubmed/15719057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030041
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC546329/
https://ncbi.nlm.nih.gov/pubmed/15719057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030041

Registos relacionados