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Basolateral membrane expression of a K(+) channel, Kir 2.3, is directed by a cytoplasmic COOH-terminal domain

The inwardly rectifying potassium channel Kir 2.3 is specifically targeted and expressed on the basolateral membrane of certain renal epithelial cells. In the present study, the structural basis for polarized targeting was elucidated. Deletion of a unique COOH-terminal domain produced channels that...

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Detalhes bibliográficos
Main Authors: Le Maout, Sophie, Welling, Paul A., Brejon, Manuel, Olsen, Olav, Merot, Jean
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC56985/
https://ncbi.nlm.nih.gov/pubmed/11504929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181481098
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