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Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate

Protein kinases of the Akt and related serum- and glucocorticoid-regulated kinase (SGK) families are major downstream mediators of phosphatidylinositol (PI) 3-kinase signaling to many cellular processes including metabolic flux, membrane trafficking, and apoptosis. Activation of these kinases is tho...

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Detalhes bibliográficos
Main Authors: Virbasius, Joseph V., Song, Xi, Pomerleau, Darcy P., Zhan, Yong, Zhou, G. Wayne, Czech, Michael P.
Formato: Artigo
Idioma:en
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60798/
https://ncbi.nlm.nih.gov/pubmed/11606732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221352898
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