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Mechanism of Suppression of the Raf/MEK/Extracellular Signal-Regulated Kinase Pathway by the Raf Kinase Inhibitor Protein

We have recently identified the Raf kinase inhibitor protein (RKIP) as a physiological endogenous inhibitor of the Raf-1/MEK/extracellular signal-regulated kinase (ERK) pathway. RKIP interfered with MEK phosphorylation and activation by Raf-1, resulting in the suppression of both Raf-1-induced trans...

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Detalhes bibliográficos
Main Authors:	Yeung, Kam, Janosch, Petra, McFerran, Brian, Rose, David W., Mischak, Harald, Sedivy, John M., Kolch, Walter, Vaneechoutte, Mario, Vauterin, Luc, van Harsselaar, Barbara, Dijkshoorn, Lenie, De Vos, Paul, Beck, R., Westdörp, I., Jahn, G., Schäfer, H., Kanz, L., Einsele, H., Nogales, Carmen, Bernal, Samuel, Chávez, Mónica, Kearns, Angela M., Freeman, Roger, Murphy, Olive M., Seiders, Penelope R., Steward, Michael, Wheeler, Janice, Zou, Lee, Stillman, Bruce, Hernandez, Eric, Ramisse, Françoise, Cavallo, Jean-Didier, Navarro-Marí, José M., Sanbonmatsu-Gámez, Sara, Pérez-Ruiz, Mercedes, Rosa-Fraile, Manuel De La, Luo, Hong, Chaudhuri, Asok, Zbrzezna, Valerie, He, Yu, Pogo, A. Oscar, Giangrande, Paloma H., A. Kimbrel, Erin, Edwards, Dean P., McDonnell, Donald P., Buvoli, Massimo, Buvoli, Ada, Leinwand, Leslie A., Gross, Atan, Pilcher, Kirsten, Blachly-Dyson, Elizabeth, Basso, Emy, Jockel, Jennifer, Bassik, Michael C., Korsmeyer, Stanley J., Forte, Michael, Dallas, Peter B., Pacchione, Stephen, Wilsker, Deborah, Bowrin, Valerie, Kobayashi, Ryuji, Moran, Elizabeth, Dronkert, Mies L. G., Beverloo, H. Berna, Johnson, Roger D., Hoeijmakers, Jan H. J., Jasin, Maria, Kanaar, Roland, Datta, Pran K., Moses, Harold L., Rui, Liangyou, Gunter, David R., Herrington, James, Carter-Su, Christin, Nakamura, Takuro, Yamazaki, Yukari, Saiki, Yuriko, Moriyama, Masatsugu, Largaespada, David A., Jenkins, Nancy A., Copeland, Neal G., Horard, Béatrice, Tatout, Christophe, Poux, Sylvain, Pirrotta, Vincenzo, Peirano, Reto I., Goerich, Derk E., Riethmacher, Dieter, Wegner, Michael, Lane, Heidi A., Beuvink, Iwan, Motoyama, Andrea B., Daly, John M., Neve, Richard M., Hynes, Nancy E., Ashcroft, Margaret, Taya, Yoichi, Vousden, Karen H., Wang, Shao-Win, Toda, Takashi, MacCallum, Robert, Harris, Adrian L., Norbury, Chris, Rodríguez-Peña, José Manuel, Cid, Víctor J., Arroyo, Javier, Nombela, César, Lawlor, Margaret A., Feng, Xiuhong, Everding, Daniel R., Sieger, Kerry, Stewart, Claire E. H., Rotwein, Peter, Akiyama, Nobutake, Matsuo, Yoshiyuki, Sai, Heitetsu, Noda, Makoto, Kizaka-Kondoh, Shinae, Calvo, Katherine R., Sykes, David B., Pasillas, Martina, Kamps, Mark P., Lombard, David B., Beard, Caroline, Johnson, Brad, Marciniak, Robert A., Dausman, Jessie, Bronson, Roderick, Buhlmann, Janet E., Lipman, Ruth, Curry, Ruth, Sharpe, Arlene, Jaenisch, Rudolf, Guarente, Leonard, Huang, Hsiang-Po, Liu, Min, El-Hodiri, Heithem M., Chu, Khoi, Jamrich, Milan, Tsai, Ming-Jer, Piras, Graziella, El Kharroubi, Aboubaker, Kozlov, Serguei, Escalante-Alcalde, Diana, Hernandez, Lidia, Gilbert, Debra J., Stewart, Colin L., Müller, Carsten, Readhead, Carol, Diederichs, Sven, Idos, Gregory, Yang, Rong, Tidow, Nicola, Serve, Hubert, Berdel, Wolfgang E., Koeffler, H. Phillip, Roberson, Mark S., Ban, Makiko, Zhang, Tong, Mulvaney, Jennifer M., Yang, Liu, Embree, Lisa J., Hickstein, Dennis D., Espeso, Eduardo A., Arst, Herbert N., Villard, Jean, Peretti, Marie, Masternak, Krzysztof, Barras, Emmanuèle, Caretti, Giuseppina, Mantovani, Roberto, Reith, Walter, Pise-Masison, Cynthia A., Mahieux, Renaud, Jiang, Hua, Radonovich, Michael, Duvall, Janet, Guillerm, Claire, Brady, John N., Saharinen, Pipsa, Takaluoma, Kati, Silvennoinen, Olli, Manes, Gaël, Bello, Paul, Roche, Serge, Rebollo, Angelita, Dumoutier, Laure, Renauld, Jean-Christophe, Zaballos, Angel, Ayllón, Verónica, Martínez-A., Carlos, Wang, Dawei, Russell, Jamie L., Johnson, David G., McHugh, Peter J., Sones, William R., Hartley, John A., Arnaud, Philippe, Goubely, Chantal, Pélissier, Thierry, Deragon, Jean-Marc, Gangolli, Esha A., Belyamani, Mouna, Muchinsky, Sara, Narula, Anita, Burton, Kimberly A., McKnight, G. Stanley, Uhler, Michael D., Idzerda, Rejean L., Nasar, Farooq, Jankowski, Craig, Nag, Dilip K., Tanaka, Koichi, Yonekawa, Toshihiro, Kawasaki, Yosuke, Kai, Mihoko, Furuya, Kanji, Iwasaki, Masaomi, Murakami, Hiroshi, Yanagida, Mitsuhiro, Okayama, Hiroto, Gachon, Frederic, Thebault, Sabine, Peleraux, Annick, Devaux, Christian, Mesnard, Jean-Michel, Kamikura, Darren M., Khoury, Hanane, Maroun, Christiane, Naujokas, Monica A., Park, Morag, Santoni-Rugiu, Eric, Falck, Jacob, Mailand, Niels, Bartek, Jiri, Lukas, Jiri, Plafker, Kendra, Macara, Ian G., Torres-Ramos, Carlos A., Johnson, Robert E., Prakash, Louise, Prakash, Satya, Zheng, Lei, Chen, Yumay, Riley, Daniel J., Chen, Phang-Lang, Lee, Wen-Hwa
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	American Society for Microbiology 2000
Assuntos:	Cell Growth and Development Letters to the Editor DNA Dynamics and Chromosome Structure Errata Mammalian Genetic Models with Minimal or Complex Phenotypes Transcriptional Regulation Gene Expression Nucleocytoplasmic Communication
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC85596/ https://ncbi.nlm.nih.gov/pubmed/10757792 https://ncbi.nlm.nih.gov/pmc/articles/PMC85597/ https://ncbi.nlm.nih.gov/pubmed/10515737 https://ncbi.nlm.nih.gov/pmc/articles/PMC85598/ https://ncbi.nlm.nih.gov/pubmed/10515738 https://ncbi.nlm.nih.gov/pmc/articles/PMC85599/ https://ncbi.nlm.nih.gov/pubmed/10515739 https://ncbi.nlm.nih.gov/pmc/articles/PMC85600/ https://ncbi.nlm.nih.gov/pubmed/10515740 https://ncbi.nlm.nih.gov/pmc/articles/PMC85601/ https://ncbi.nlm.nih.gov/pubmed/10757793 https://ncbi.nlm.nih.gov/pmc/articles/PMC85602/ https://ncbi.nlm.nih.gov/pubmed/10515741 https://ncbi.nlm.nih.gov/pmc/articles/PMC85603/ https://ncbi.nlm.nih.gov/pmc/articles/PMC85604/ https://ncbi.nlm.nih.gov/pubmed/10757794 https://ncbi.nlm.nih.gov/pmc/articles/PMC85605/ https://ncbi.nlm.nih.gov/pubmed/10757795 https://ncbi.nlm.nih.gov/pmc/articles/PMC85606/ https://ncbi.nlm.nih.gov/pubmed/10757796 https://ncbi.nlm.nih.gov/pmc/articles/PMC85607/ https://ncbi.nlm.nih.gov/pubmed/10757797 https://ncbi.nlm.nih.gov/pmc/articles/PMC85608/ https://ncbi.nlm.nih.gov/pubmed/10757798 https://ncbi.nlm.nih.gov/pmc/articles/PMC85609/ https://ncbi.nlm.nih.gov/pubmed/10757799 https://ncbi.nlm.nih.gov/pmc/articles/PMC85610/ https://ncbi.nlm.nih.gov/pubmed/10757800 https://ncbi.nlm.nih.gov/pmc/articles/PMC85611/ https://ncbi.nlm.nih.gov/pubmed/10757801 https://ncbi.nlm.nih.gov/pmc/articles/PMC85612/ https://ncbi.nlm.nih.gov/pubmed/10757802 https://ncbi.nlm.nih.gov/pmc/articles/PMC85613/ https://ncbi.nlm.nih.gov/pubmed/10757803 https://ncbi.nlm.nih.gov/pmc/articles/PMC85614/ https://ncbi.nlm.nih.gov/pubmed/10757804 https://ncbi.nlm.nih.gov/pmc/articles/PMC85615/ https://ncbi.nlm.nih.gov/pubmed/10757805 https://ncbi.nlm.nih.gov/pmc/articles/PMC85616/ https://ncbi.nlm.nih.gov/pubmed/10757806 https://ncbi.nlm.nih.gov/pmc/articles/PMC85617/ https://ncbi.nlm.nih.gov/pubmed/10757807 https://ncbi.nlm.nih.gov/pmc/articles/PMC85618/ https://ncbi.nlm.nih.gov/pubmed/10757808 https://ncbi.nlm.nih.gov/pmc/articles/PMC85619/ https://ncbi.nlm.nih.gov/pubmed/10757809 https://ncbi.nlm.nih.gov/pmc/articles/PMC85620/ https://ncbi.nlm.nih.gov/pubmed/10757810 https://ncbi.nlm.nih.gov/pmc/articles/PMC85621/ https://ncbi.nlm.nih.gov/pubmed/10757811 https://ncbi.nlm.nih.gov/pmc/articles/PMC85622/ https://ncbi.nlm.nih.gov/pubmed/10757812 https://ncbi.nlm.nih.gov/pmc/articles/PMC85623/ https://ncbi.nlm.nih.gov/pubmed/10757813 https://ncbi.nlm.nih.gov/pmc/articles/PMC85624/ https://ncbi.nlm.nih.gov/pubmed/10757814 https://ncbi.nlm.nih.gov/pmc/articles/PMC85625/ https://ncbi.nlm.nih.gov/pubmed/10757815 https://ncbi.nlm.nih.gov/pmc/articles/PMC85626/ https://ncbi.nlm.nih.gov/pubmed/10779323 https://ncbi.nlm.nih.gov/pmc/articles/PMC85627/ https://ncbi.nlm.nih.gov/pubmed/10779324 https://ncbi.nlm.nih.gov/pmc/articles/PMC85628/ https://ncbi.nlm.nih.gov/pubmed/10779325 https://ncbi.nlm.nih.gov/pmc/articles/PMC85629/ https://ncbi.nlm.nih.gov/pubmed/10779326 https://ncbi.nlm.nih.gov/pmc/articles/PMC85630/ https://ncbi.nlm.nih.gov/pubmed/10779327 https://ncbi.nlm.nih.gov/pmc/articles/PMC85631/ https://ncbi.nlm.nih.gov/pubmed/10779328 https://ncbi.nlm.nih.gov/pmc/articles/PMC85632/ https://ncbi.nlm.nih.gov/pubmed/10779329 https://ncbi.nlm.nih.gov/pmc/articles/PMC85633/ https://ncbi.nlm.nih.gov/pubmed/10779330 https://ncbi.nlm.nih.gov/pmc/articles/PMC85634/ https://ncbi.nlm.nih.gov/pubmed/10779331 https://ncbi.nlm.nih.gov/pmc/articles/PMC85635/ https://ncbi.nlm.nih.gov/pubmed/10779332 https://ncbi.nlm.nih.gov/pmc/articles/PMC85636/ https://ncbi.nlm.nih.gov/pubmed/10779333 https://ncbi.nlm.nih.gov/pmc/articles/PMC85637/ https://ncbi.nlm.nih.gov/pubmed/10779334 https://ncbi.nlm.nih.gov/pmc/articles/PMC85638/ https://ncbi.nlm.nih.gov/pubmed/10779335 https://ncbi.nlm.nih.gov/pmc/articles/PMC85639/ https://ncbi.nlm.nih.gov/pubmed/10779336 https://ncbi.nlm.nih.gov/pmc/articles/PMC85640/ https://ncbi.nlm.nih.gov/pubmed/10779337 https://ncbi.nlm.nih.gov/pmc/articles/PMC85641/ https://ncbi.nlm.nih.gov/pubmed/10779338 https://ncbi.nlm.nih.gov/pmc/articles/PMC85642/ https://ncbi.nlm.nih.gov/pubmed/10779339 https://ncbi.nlm.nih.gov/pmc/articles/PMC85643/ https://ncbi.nlm.nih.gov/pubmed/10779340 https://ncbi.nlm.nih.gov/pmc/articles/PMC85644/ https://ncbi.nlm.nih.gov/pubmed/10779341 https://ncbi.nlm.nih.gov/pmc/articles/PMC85645/ https://ncbi.nlm.nih.gov/pubmed/10779342
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Mechanism of Suppression of the Raf/MEK/Extracellular Signal-Regulated Kinase Pathway by the Raf Kinase Inhibitor Protein

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