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Functional Measurement of Hepatitis C Virus Core-Specific CD8(+) T-Cell Responses in the Livers or Peripheral Blood of Patients by Using Autologous Peripheral Blood Mononuclear Cells as Targets or Stimulators

As is widely recognized, CD8(+) cytotoxic T lymphocytes (CTLs) play a crucial role in hepatitis C virus (HCV) infection, both in pathogenesis of liver injury and in clearing the virus. CTL studies with HCV-infected patients have been difficult because of the relatively low frequency of CTL precursor...

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Detalhes bibliográficos
Main Authors: Fang, Shih-Hua, Chiang, Bor-Luen, Wu, Mei-Hua, Iba, Hideo, Lai, Ming-Yang, Yang, Pei-Ming, Chen, Ding-Shinn, Hwang, Lih-Hwa
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC88461/
https://ncbi.nlm.nih.gov/pubmed/11682504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.39.11.3895-3901.2001
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