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Contribution of Natural Amino Acid Substitutions in SHV Extended-Spectrum β-Lactamases to Resistance against Various β-Lactams

SHV extended-spectrum β-lactamases (ESBLs) arise through single amino acid substitutions in the parental enzyme, SHV-1. In order to evaluate the effect of genetic dissimilarities around the structural gene on MICs, we had previously devised an isogenic system of strains. Here, we present an extended...

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Detalhes bibliográficos
Main Authors:	Randegger, Corinne C., Keller, André, Irla, Michel, Wada, Akihito, Hächler, Herbert, Gozalbes, Rafael, Brun-Pascaud, Monique, García-Domenech, Ramon, Gálvez, Jorge, Girard, Pierre-Marie, Doucet, Jean-Pierre, Derouin, Francis, Garcia-Domenech, Ramon, Galvez, Jorge, Winokur, P. L., Brueggemann, A., DeSalvo, D. L., Hoffmann, L., Apley, M. D., Uhlenhopp, E. K., Pfaller, M. A., Doern, G. V., Suling, William J., Seitz, Lainne E., Pathak, Vibha, Westbrook, Louise, Barrow, Esther W., Zywno-van-Ginkel, Sabrina, Reynolds, Robert C., Piper, J. Robert, Barrow, William W., Achenbach, Tatjana V., Slater, Emily P., Brummerhop, Harm, Bach, Thorsten, Müller, Rolf, Caldelari, I., Loeliger, B., Langen, H., Glauser, M. P., Moreillon, P., Pescovitz, Mark D., Rabkin, John, Merion, Robert M., Paya, Carlos V., Pirsch, John, Freeman, R. B., O'Grady, John, Robinson, Charles, To, Zung, Wren, Kristina, Banken, Ludger, Buhles, William, Brown, Frances, Smith, Patrick F., Forrest, Alan, Ballow, Charles H., Martin, David E., Proulx, Louise, Lipsitch, Marc, Bacon, Teresa H., Leary, Jeffry J., Antia, Rustom, Levin, Bruce R., Benoit-Vical, Françoise, Robert, Anne, Meunier, Bernard, Giacometti, A., Cirioni, O., Ghiselli, R., Goffi, L., Viticchi, C., Mocchegiani, F., Riva, A., Orlando, F., Saba, V., Scalise, G., Peschel, Andreas, Vuong, Cuong, Otto, Michael, Götz, Friedrich, Rastogi, Nalin, Goh, Khye Seng, Berchel, Mylene, Bryskier, André, Watanabe, T., Takano, M., Ogasawara, A., Mikami, T., Kobayashi, T., Watabe, M., Matsumoto, T., Høiby, Niels, Pers, Charlotte, Johansen, Helle Krogh, Hansen, Hanne, Cloeckaert, Axel, Baucheron, Sylvie, Flaujac, Geraldine, Schwarz, Stefan, Kehrenberg, Corinna, Martel, Jean-Louis, Chaslus-Dancla, Elisabeth, Pumbwe, Lilian, Piddock, Laura J. V., Kirkpatrick, William R., McAtee, Robert K., Fothergill, Annette W., Rinaldi, Michael G., Patterson, Thomas F., Kawamura-Sato, Kumiko, Iinuma, Yoshitsugu, Hasegawa, Tadao, Horii, Toshinobu, Yamashino, Takafumi, Ohta, Michio, McLain, Nealoo, Ascanio, Rhoda, Baker, Carol, Strohaver, Robert A., Dolan, Joseph W., Kao, Susan J., You, Il, Clewell, Don B., Donabedian, Susan M., Zervos, Marcus J., Petrin, Joanne, Shaw, Karen J., Chow, Joseph W., Fuchs, Peter C., Barry, Arthur L., Brown, Steven D., Yamazumi, T., Messer, S. A., Houston, A., Hollis, R. J., Jones, R. N., Gunderson, Shana M., Hoffman, Holly, Ernst, Erika J., Pfaller, Michael A., Klepser, Michael E., Waters, W. R., Frydman, B., Marton, L. J., Valasinas, A., Reddy, V. K., Harp, J. A., Wannemuehler, M. J., Yarlett, N., Cynamon, M. H., Carter, J. L., Shoen, C. M., White, David G., Maurer, John J., Zhao, Shaohua, Ricci, Vito, Thayer, Stephan G., Adedoyin, Adedayo, Swenson, Christine E., Bolcsak, Lois E., Hellmann, Andrzej, Radowska, Danuta, Horwith, Gary, Janoff, Andrew S., Branch, Robert A., Castro, Nelly, Medina, Roberto, Sotelo, Julio, Jung, Helgi, Xiong, A., Gottman, A., Park, C., Baetens, M., Pandza, S., Matin, A., Kim, Wan-Seop, Wang, Yi, Fang, Aiqi, Demain, Arnold L., Villa, Laura, Pezzella, Cristina, Tosini, Fabio, Visca, Paolo, Petrucca, Andrea, Carattoli, Alessandra, Kontoyiannis, Dimitrios P., Lewis, Russell E., Sagar, Namita, May, Gregory, Prince, Randall A., Rolston, Kenneth V. I., Consigny, Sophie, Bentoucha, Abdelhalim, Bonnafous, Pascale, Grosset, Jacques, Ji, Baohong, Jones, Ronald N., Walsh, Thomas J., Jackson, Andre J., Lee, James W., Amantea, Michael, Sein, Tin, Bacher, John, Zech, Loren, Urbina, Julio A., Lira, Renee, Visbal, Gonzalo, Bartrolí, Javier, Almeida, Jonas S, Vinga, Susana, Kotra, Lakshmi P., Haddad, Jalal, Mobashery, Shahriar, Lupetti, Antonella, Paulusma-Annema, Akke, Welling, Mick M., Senesi, Sonia, van Dissel, Jaap T., Nibbering, Peter H., Giamarellou, Helen, Bassaris, Harry P., Petrikkos, George, Busch, Wilhelm, Voulgarelis, Michel, Antoniadou, Anastasia, Grouzi, Elisabeth, Zoumbos, Nikolaos, Paek, Kyong-Sook, Kim, Mu-Yong, Lee, Chang-Seok, Youn, Hasik, Kira, Toshihiko, Grill, Susan P., Dutschman, Ginger E., Lin, Ju-Sheng, Qu, Fucheng, Choi, Yongseok, Chu, Chung K., Cheng, Yung-Chi, Donald, P. R., Sirgel, F. A., Kanyok, T. P., Danziger, L. H., Venter, A., Botha, F. J., Parkin, D. P., Seifart, H. I., Van de Wal, B. W., Maritz, J. S., Mitchison, D. A., Dreses-Werringloer, Ute, Padubrin, Ingrid, Jürgens-Saathoff, Barbara, Hudson, Alan P., Zeidler, H., Köhler, L., Morlock, Glenn P., Plikaytis, Bonnie B., Crawford, Jack T., Chiller, Tom, Farrokhshad, Kouros, Brummer, Elmer, Stevens, David A., Giacometti, Andrea, Cirioni, Oscar, Ghiselli, Roberto, Goffi, Luigi, Mocchegiani, Federico, Riva, Alessandra, Scalise, Giorgio, Saba, Vittorio
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	American Society for Microbiology 2000
Assuntos:	Mechanisms of Resistance Mechanisms of Action: Physiological Effects Susceptibility Pharmacology Antiviral Agents Experimental Therapeutics Chemistry; Biosynthesis Letters to the Editor Errata Methodology article Minireviews Clinical Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC90148/ https://ncbi.nlm.nih.gov/pubmed/10991857 https://ncbi.nlm.nih.gov/pmc/articles/PMC90149/ https://ncbi.nlm.nih.gov/pubmed/10991858 https://ncbi.nlm.nih.gov/pmc/articles/PMC90150/ https://ncbi.nlm.nih.gov/pubmed/10991859 https://ncbi.nlm.nih.gov/pmc/articles/PMC90151/ https://ncbi.nlm.nih.gov/pubmed/10991860 https://ncbi.nlm.nih.gov/pmc/articles/PMC90152/ https://ncbi.nlm.nih.gov/pubmed/10991861 https://ncbi.nlm.nih.gov/pmc/articles/PMC90153/ https://ncbi.nlm.nih.gov/pubmed/10991862 https://ncbi.nlm.nih.gov/pmc/articles/PMC90154/ https://ncbi.nlm.nih.gov/pubmed/10991863 https://ncbi.nlm.nih.gov/pmc/articles/PMC90155/ https://ncbi.nlm.nih.gov/pubmed/10991864 https://ncbi.nlm.nih.gov/pmc/articles/PMC90156/ https://ncbi.nlm.nih.gov/pubmed/10991865 https://ncbi.nlm.nih.gov/pmc/articles/PMC90157/ https://ncbi.nlm.nih.gov/pubmed/10991866 https://ncbi.nlm.nih.gov/pmc/articles/PMC90158/ https://ncbi.nlm.nih.gov/pubmed/10991867 https://ncbi.nlm.nih.gov/pmc/articles/PMC90159/ https://ncbi.nlm.nih.gov/pubmed/10991868 https://ncbi.nlm.nih.gov/pmc/articles/PMC90160/ https://ncbi.nlm.nih.gov/pubmed/10991869 https://ncbi.nlm.nih.gov/pmc/articles/PMC90161/ https://ncbi.nlm.nih.gov/pubmed/10991870 https://ncbi.nlm.nih.gov/pmc/articles/PMC90162/ https://ncbi.nlm.nih.gov/pubmed/10991871 https://ncbi.nlm.nih.gov/pmc/articles/PMC90163/ https://ncbi.nlm.nih.gov/pubmed/10991872 https://ncbi.nlm.nih.gov/pmc/articles/PMC90164/ https://ncbi.nlm.nih.gov/pubmed/10991873 https://ncbi.nlm.nih.gov/pmc/articles/PMC90165/ https://ncbi.nlm.nih.gov/pubmed/10991874 https://ncbi.nlm.nih.gov/pmc/articles/PMC90166/ https://ncbi.nlm.nih.gov/pubmed/10991875 https://ncbi.nlm.nih.gov/pmc/articles/PMC90167/ https://ncbi.nlm.nih.gov/pubmed/10991876 https://ncbi.nlm.nih.gov/pmc/articles/PMC90168/ https://ncbi.nlm.nih.gov/pubmed/10991877 https://ncbi.nlm.nih.gov/pmc/articles/PMC90169/ https://ncbi.nlm.nih.gov/pubmed/10991878 https://ncbi.nlm.nih.gov/pmc/articles/PMC90170/ https://ncbi.nlm.nih.gov/pubmed/10991879 https://ncbi.nlm.nih.gov/pmc/articles/PMC90171/ https://ncbi.nlm.nih.gov/pubmed/10991880 https://ncbi.nlm.nih.gov/pmc/articles/PMC90172/ https://ncbi.nlm.nih.gov/pubmed/10991881 https://ncbi.nlm.nih.gov/pmc/articles/PMC90173/ https://ncbi.nlm.nih.gov/pubmed/10991882 https://ncbi.nlm.nih.gov/pmc/articles/PMC90174/ https://ncbi.nlm.nih.gov/pubmed/10991883 https://ncbi.nlm.nih.gov/pmc/articles/PMC90175/ https://ncbi.nlm.nih.gov/pubmed/10991884 https://ncbi.nlm.nih.gov/pmc/articles/PMC90176/ https://ncbi.nlm.nih.gov/pubmed/10991885 https://ncbi.nlm.nih.gov/pmc/articles/PMC90177/ https://ncbi.nlm.nih.gov/pubmed/10991886 https://ncbi.nlm.nih.gov/pmc/articles/PMC90178/ https://ncbi.nlm.nih.gov/pubmed/10991887 https://ncbi.nlm.nih.gov/pmc/articles/PMC90179/ https://ncbi.nlm.nih.gov/pubmed/10991888 https://ncbi.nlm.nih.gov/pmc/articles/PMC90180/ https://ncbi.nlm.nih.gov/pubmed/10991889 https://ncbi.nlm.nih.gov/pmc/articles/PMC90181/ https://ncbi.nlm.nih.gov/pubmed/10991890 https://ncbi.nlm.nih.gov/pmc/articles/PMC90182/ https://ncbi.nlm.nih.gov/pubmed/10991891 https://ncbi.nlm.nih.gov/pmc/articles/PMC90183/ https://ncbi.nlm.nih.gov/pubmed/11203420 https://ncbi.nlm.nih.gov/pmc/articles/PMC90184/ https://ncbi.nlm.nih.gov/pmc/articles/PMC90185/ https://ncbi.nlm.nih.gov/pmc/articles/PMC90186/ https://ncbi.nlm.nih.gov/pmc/articles/PMC90187/ https://ncbi.nlm.nih.gov/pubmed/11895567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-3-6 https://ncbi.nlm.nih.gov/pmc/articles/PMC90188/ https://ncbi.nlm.nih.gov/pubmed/11083623 https://ncbi.nlm.nih.gov/pmc/articles/PMC90189/ https://ncbi.nlm.nih.gov/pubmed/11083624 https://ncbi.nlm.nih.gov/pmc/articles/PMC90190/ https://ncbi.nlm.nih.gov/pubmed/11083625 https://ncbi.nlm.nih.gov/pmc/articles/PMC90191/ https://ncbi.nlm.nih.gov/pubmed/11083626 https://ncbi.nlm.nih.gov/pmc/articles/PMC90192/ https://ncbi.nlm.nih.gov/pubmed/11083627 https://ncbi.nlm.nih.gov/pmc/articles/PMC90193/ https://ncbi.nlm.nih.gov/pubmed/11083628 https://ncbi.nlm.nih.gov/pmc/articles/PMC90194/ https://ncbi.nlm.nih.gov/pubmed/11083629 https://ncbi.nlm.nih.gov/pmc/articles/PMC90195/ https://ncbi.nlm.nih.gov/pubmed/11083630 https://ncbi.nlm.nih.gov/pmc/articles/PMC90196/ https://ncbi.nlm.nih.gov/pubmed/11083631 https://ncbi.nlm.nih.gov/pmc/articles/PMC90197/ https://ncbi.nlm.nih.gov/pubmed/11083632
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