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Anti-Human Immunodeficiency Virus Activity of YK-FH312 (a Betulinic Acid Derivative), a Novel Compound Blocking Viral Maturation

Betulinic acid, a triterpenoid isolated from the methyl alcohol extract of the leaves of Syzigium claviflorum, was found to have a potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). Betulinic acid derivatives were synthesized to enhance the anti-HIV activity. Among the d...

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Detalhes bibliográficos
Main Authors: Kanamoto, Taisei, Kashiwada, Yoshiki, Kanbara, Kenji, Gotoh, Kazuyo, Yoshimori, Manabu, Goto, Toshiyuki, Sano, Kouichi, Nakashima, Hideki
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90447/
https://ncbi.nlm.nih.gov/pubmed/11257038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1225-1230.2001
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