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Subunit Vaccination of Mice against New World Cutaneous Leishmaniasis: Comparison of Three Proteins Expressed in Amastigotes and Six Adjuvants

A mixture of well-defined recombinant antigens together with an adjuvant that preferentially stimulates specific gamma interferon (IFN-γ)-secreting helper type 1 CD4(+) T cells (Th1 cells) presents a rational option for a vaccine against leishmaniasis. The potential of this approach was investigated...

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Detalhes bibliográficos
Main Authors: Aebischer, Toni, Wolfram, Markus, Patzer, Silke I., Ilg, Thomas, Wiese, Martin, Overath, Peter
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97286/
https://ncbi.nlm.nih.gov/pubmed/10678945
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