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Immunization with Recombinant Opc Outer Membrane Protein from Neisseria meningitidis: Influence of Sequence Variation and Levels of Expression on the Bactericidal Immune Response against Meningococci

The opc gene from Neisseria meningitidis was cloned into the pRSETA vector, and recombinant protein was expressed at high levels in Escherichia coli. The protein was readily purified by affinity chromatography and used for immunization with conventional Al(OH)(3) adjuvant or after incorporation into...

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Detalhes bibliográficos
Main Authors:	Jolley, Keith A., Appleby, Lynn, Wright, J. Claire, Christodoulides, Myron, Heckels, John E., Zaitseva, Marina, King, Lisa R., Manischewitz, Jody, Dougan, Michael, Stevan, Lee, Golding, Hana, Golding, Basil, Wang, Jin Yuan, Noriega, Fernando R., Galen, James E., Barry, Eileen, Levine, Myron M., Zhang, Ying, Masi, Amy W., Barniak, Vicki, Mountzouros, Ken, Hostetter, Margaret K., Green, Bruce A., Gobert, Alain P., Daulouede, Sylvie, Lepoivre, Michel, Boucher, Jean Luc, Bouteille, Bernard, Buguet, Alain, Cespuglio, Raymond, Veyret, Bernard, Vincendeau, Philippe, van Schilfgaarde, Muriel, van Ulsen, Peter, Eijk, Paul, Brand, Michiel, Stam, Martin, Kouame, Jamal, van Alphen, Loek, Dankert, Jacob, Mu, Hong-Hua, Sawitzke, Allen D., Cole, Barry C., Samsom, Janneke N., Annema, Akke, Geertsma, Minke F., Langermans, Jan A. M., Groeneveld, Paul H. P., de Heer, Emile, van Furth, Ralph, Brahimi, Karima, Badell, Edgar, Sauzet, Jean-Pierre, BenMohamed, Lbachir, Daubersies, Pierre, Guérin-Marchand, Claudine, Snounou, George, Druilhe, Pierre, Taylor, Philip R., Seixas, Elsa, Walport, Mark J., Langhorne, Jean, Botto, Marina, West, Nicholas P., Jungnitz, Heidrun, Fitter, John T., McArthur, Jason D., Guzmán, Carlos A., Walker, Mark J., Blackwell, Nathan M., Else, Kathryn J., Hou, Linda, Sasaki, Hajime, Stashenko, Philip, Hardy, Robert D., Jafri, Hasan S., Olsen, Kurt, Wordemann, Meike, Hatfield, Jeanine, Rogers, Beverly B., Patel, Padma, Duffy, Lynn, Cassell, Gail, McCracken, George H., Ramilo, Octavio, Kozar, Michael P., Krahmer, Mark T., Fox, Alvin, Gray, Barry M., Mattsson, Eva, Herwald, Heiko, Cramer, Henning, Persson, Kristin, Sjöbring, Ulf, Björck, Lars, Mercier, Renee-Claude, Rybak, Michael J., Bayer, Arnold S., Yeaman, Michael R., Tanida, Toyohiro, Rao, Fu, Hamada, Toshihiro, Ueta, Eisaku, Osaki, Tokio, Van Kirk, Levi S., Hayes, Stanley F., Heinzen, Robert A., Jackson, Graham D. F., Dai, Yung, Sewell, William A., Padol, Ireneusz T., Moran, Anthony P., Hunt, Richard H., Sanchez, Gloria I., Sedegah, Martha, Rogers, William O., Jones, Trevor R., Sacci, John, Witney, Adam, Carucci, Daniel J., Kumar, Nirbhay, Hoffman, Stephen L., Tang, Xing, Lasbury, Mark E., Davidson, Darrell D., Bartlett, Marilyn S., Smith, James W., Lee, Chao-Hung, Manimtim, Winston M., Hasday, Jeffrey D., Hester, Lisa, Fairchild, Karen D., Lovchik, Judith C., Viscardi, Rose M., Cornelissen, Cynthia Nau, Anderson, James E., Boulton, Ian C., Sparling, P. Frederick, Manning-Cela, Rebeca, Cortés, Arantxa, González-Rey, Elena, Van Voorhis, Wesley C., Swindle, John, González, Antonio, Le Cabec, Véronique, Cols, Carine, Maridonneau-Parini, Isabelle, Gahan, Cormac G. M., O'Mahony, James, Hill, Colin, Graves, Dana T., Chen, Chih-Ping, Douville, Christopher, Jiang, Yanling, Morrison, Daniel F., Foss, Dennis L., Murtaugh, Michael P., Kougias, Panagiotis, Wei, Duo, Rice, Peter J., Ensley, Harry E., Kalbfleisch, John, Williams, David L., Browder, I. William, Huh, Won-Ki, Kim, Seong-Tae, Kim, Hyungsoo, Jeong, Gajin, Kang, Sa-Ouk, Hagman, Kayla E., Yang, Xiaofeng, Wikel, Stephen K., Schoeler, George B., Caimano, Melissa J., Radolf, Justin D., Norgard, Michael V., Blessing, Erwin, Lin, Tsun-Mei, Campbell, Lee Ann, Rosenfeld, Michael E., Lloyd, Deborah, Kuo, Cho-chou, Matsunaga, Kazuto, Klein, Thomas W., Friedman, Herman, Yamamoto, Yoshimasa, Rossi, Giacomo, Fortuna, Damiano, Pancotto, Laura, Renzoni, Giacomo, Taccini, Ennio, Ghiara, Paolo, Rappuoli, Rino, Del Giudice, Giuseppe, Rippere-Lampe, Karen E., O'Brien, Alison D., Conran, Richard, Lockman, Hank A., Yamamoto, Yasuhito, Sato, Yutaka, Takahashi-Abbe, Shoko, Takahashi, Nobuhiro, Kizaki, Harutoshi, Sheehan, Brian J., Langford, Paul R., Rycroft, Andrew N., Kroll, J. Simon, Wilson, Rebecca L., Elthon, Jessica, Clegg, Steven, Jones, Bradley D., Medina, Eva, Schulze, Kai, Chhatwal, Gursharan Singh, Guzmán, Carlos Alberto, López, Santiago, Marco, Alberto Jesús, Prats, Neus, Czuprynski, Charles J., van der Flier, Michiel, Coenjaerts, Frank, Kimpen, Jan L. L., Hoepelman, Andy M., Geelen, Sibyl P. M., Faruque, Shah M., Asadulghani, Rahman, M. Mostafizur, Waldor, Matthew K., Sack, David A., Sutton, Philip, Kolesnikow, Tassia, Danon, Stephen, Wilson, John, Lee, Adrian, Pais, Teresa F., Cunha, Joana Feijó, Appelberg, Rui, Epelman, Slava, Bruno, Tony F., Neely, Graham G., Woods, Donald E., Mody, Christopher H., Boursaux-Eude, Caroline, Guiso, Nicole, Veltrop, Marcel H. A. M., Bancsi, Maurice J. L. M. F., Bertina, Rogier M., Thompson, Jan, Channon, Jacqueline Y., Seguin, Rosanne M., Kasper, Lloyd H.
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	American Society for Microbiology 2001
Assuntos:	Microbial Immunity and Vaccines Fungal and Parasitic Infections Molecular and Cellular Pathogenesis Host Response and Inflammation Bacterial Infections Cellular Microbiology: Pathogen-Host Cell Molecular Interactions Molecular Pathogenesis
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Immunization with Recombinant Opc Outer Membrane Protein from Neisseria meningitidis: Influence of Sequence Variation and Levels of Expression on the Bactericidal Immune Response against Meningococci

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