Bibliotecas PUC-SP - Busca Integrada

Evolving our understanding of cancer: an interview with Charles Swanton

Por Charles Swanton
Publicado no Disease Models & Mechanisms (2025-03-01)

ctDNA: An emerging neoadjuvant biomarker in resectable solid tumors.

Por Christopher Abbosh, Charles Swanton
Publicado no PLoS Medicine (2021-10-01)

The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome

Por Deborah R. Caswell, Charles Swanton
Publicado no BMC Medicine (2017-07-01)

Review: Systemic therapy for advanced renal cell carcinoma

Por James M.G. Larkin, Emma L.S. Kipps, Ceri J. Powell, Charles Swanton
Publicado no Therapeutic Advances in Medical Oncology (2009-07-01)

Clinical referral to the NHS following multi-cancer early detection test results from the NHS-Galleri trial

Por Ian Lowenhoff, Saoirse Dolly, Rebecca Dowinton Smith, Sara Hiom, Liz Holmes, Peter Johnson, Laura King, Richard D. Neal, Thomas Round, Charles Swanton, Charles Swanton, Lennard Y. W. Lee, Lennard Y. W. Lee
Publicado no Frontiers in Oncology (2025-05-01)

APOBEC3 as a driver of genetic intratumor heterogeneity

Por Subramanian Venkatesan, Mihaela Angelova, Jirina Bartkova, Samuel F. Bakhoum, Jiri Bartek, Nnennaya Kanu, Charles Swanton
Publicado no Molecular & Cellular Oncology (2021-12-01)

Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

Por Robert E. Hynds, Kristopher K. Frese, David R. Pearce, Eva Grönroos, Caroline Dive, Charles Swanton
Publicado no Open Biology (2021-01-01)

Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection

Por James E. Barrett, Andrew Feber, Javier Herrero, Miljana Tanic, Gareth A. Wilson, Charles Swanton, Stephan Beck
Publicado no BMC Bioinformatics (2017-07-01)

An agent-based modelling framework to study growth mechanisms in EGFR-L858R mutant cell alveolar type II cells

Por Helena Coggan, Clare E. Weeden, Philip Pearce, Mohit P. Dalwadi, Alastair Magness, Charles Swanton, Karen M. Page
Publicado no Royal Society Open Science (2024-07-01)

Cell-Free DNA–Based Multi-Cancer Early Detection Test in an Asymptomatic Screening Population (NHS-Galleri): Design of a Pragmatic, Prospective Randomised Controlled Trial

Por Richard D. Neal, Peter Johnson, Christina A. Clarke, Stephanie A. Hamilton, Nan Zhang, Harpal Kumar, Charles Swanton, Peter Sasieni
Publicado no Cancers (2022-10-01)

Cancer gene identification from RNA variant allelic frequencies using RVdriver

Por James R. M. Black, Thomas P. Jones, Carlos Martínez-Ruiz, Maria Litovchenko, Clare Puttick, Charles Swanton, Nicholas McGranahan
Publicado no Genome Biology (2025-06-01)

Minimising immunohistochemical false negative ER classification using a complementary 23 gene expression signature of ER status.

Por Qiyuan Li, Aron C Eklund, Nicolai Juul, Benjamin Haibe-Kains, Christopher T Workman, Andrea L Richardson, Zoltan Szallasi, Charles Swanton
Publicado no PLoS ONE (2010-12-01)

RAS oncogenic activity predicts response to chemotherapy and outcome in lung adenocarcinoma

Por Philip East, Gavin P. Kelly, Dhruva Biswas, Michela Marani, David C. Hancock, Todd Creasy, Kris Sachsenmeier, Charles Swanton, TRACERx consortium, Julian Downward, Sophie de Carné Trécesson
Publicado no Nature Communications (2022-09-01)

The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.

Por Attila Marcell Szász, Qiyuan Li, Aron C Eklund, Zsófia Sztupinszki, Andrew Rowan, Anna-Mária Tőkés, Borbála Székely, András Kiss, Miklós Szendrői, Balázs Győrffy, Zoltán Szállási, Charles Swanton, Janina Kulka
Publicado no PLoS ONE (2013-01-01)

Replication timing alterations are associated with mutation acquisition during breast and lung cancer evolution

Por Michelle Dietzen, Haoran Zhai, Olivia Lucas, Oriol Pich, Christopher Barrington, Wei-Ting Lu, Sophia Ward, Yanping Guo, Robert E. Hynds, Simone Zaccaria, Charles Swanton, Nicholas McGranahan, Nnennaya Kanu
Publicado no Nature Communications (2024-07-01)

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

Por David R. Pearce, David R. Pearce, Ayse U. Akarca, Roel P. H. De Maeyer, Emily Kostina, Ariana Huebner, Ariana Huebner, Ariana Huebner, Monica Sivakumar, Monica Sivakumar, Takahiro Karasaki, Kavina Shah, Sam M. Janes, Nicholas McGranahan, Nicholas McGranahan, Venkat Reddy, Arne N. Akbar, David A. Moore, David A. Moore, Teresa Marafioti, Charles Swanton, Charles Swanton, Robert E. Hynds, Robert E. Hynds, Robert E. Hynds
Publicado no Frontiers in Oncology (2023-06-01)

Refphase: Multi-sample phasing reveals haplotype-specific copy number heterogeneity.

Por Thomas B K Watkins, Emma C Colliver, Matthew R Huska, Tom L Kaufmann, Emilia L Lim, Cody B Duncan, Kerstin Haase, Peter Van Loo, Charles Swanton, Nicholas McGranahan, Roland F Schwarz
Publicado no PLoS Computational Biology (2023-10-01)

Quantifying the impact of immunotherapy on RNA dynamics in cancer

Por Yin Wu, Charles Swanton, Mihaela Angelova, Crispin Hiley, Marleen Kok, Nicolai Birkbak, Ieva Usaite, Dhruva Biswas, Krijn Dijkstra, Thomas BK Watkins, Oriol Pich, Clare Puttick, Krupa Thakkar, Simone Zaccaria, Kevin Litchfield, Nnennaya Kanu
Publicado no Journal for ImmunoTherapy of Cancer (2023-11-01)

MEDICC2: whole-genome doubling aware copy-number phylogenies for cancer evolution

Por Tom L. Kaufmann, Marina Petkovic, Thomas B. K. Watkins, Emma C. Colliver, Sofya Laskina, Nisha Thapa, Darlan C. Minussi, Nicholas Navin, Charles Swanton, Peter Van Loo, Kerstin Haase, Maxime Tarabichi, Roland F. Schwarz
Publicado no Genome Biology (2022-11-01)

Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin

Por Jan Attig, Judith Pape, Laura Doglio, Anastasiya Kazachenka, Eleonora Ottina, George R. Young, Katey S.S. Enfield, Iker Valle Aramburu, Kevin W. Ng, Nikhil Faulkner, William Bolland, Venizelos Papayannopoulos, Charles Swanton, George Kassiotis
Publicado no The Journal of Clinical Investigation (2023-07-01)