Bibliotecas PUC-SP - Busca Integrada

Fasting and time of day independently modulate circadian rhythm relevant gene expression in adipose and skin tissue

by Alexessander Couto Alves, Craig A. Glastonbury, Julia S. El-Sayed Moustafa, Kerrin S. Small
Published in BMC Genomics (2018-09-01)

Nuclear genetic regulation of the human mitochondrial transcriptome

by Aminah T Ali, Lena Boehme, Guillermo Carbajosa, Vlad C Seitan, Kerrin S Small, Alan Hodgkinson
Published in eLife (2019-02-01)

Adipose tissue gene expression and longitudinal clinical phenotypes are early biomarkers of lipid-regulating drug usage

by Max Tomlinson, Julia S. El-Sayed Moustafa, Xinyuan Zhang, Yasrab Raza, Dongmeng Wang, Alan Hodgkinson, Kerrin S. Small
Published in Scientific Reports (2025-08-01)

The rate of nonallelic homologous recombination in males is highly variable, correlated between monozygotic twins and independent of age.

by Jacqueline A L MacArthur, Timothy D Spector, Sarah J Lindsay, Massimo Mangino, Raj Gill, Kerrin S Small, Matthew E Hurles
Published in PLoS Genetics (2014-03-01)

Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable.

by Antonino Zito, Amy L Roberts, Alessia Visconti, Niccolo' Rossi, Rosa Andres-Ejarque, Stefano Nardone, Julia S El-Sayed Moustafa, Mario Falchi, Kerrin S Small
Published in PLoS Genetics (2023-02-01)

Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age

by Antonino Zito, Matthew N. Davies, Pei-Chien Tsai, Susanna Roberts, Rosa Andres-Ejarque, Stefano Nardone, Jordana T. Bell, Chloe C. Y. Wong, Kerrin S. Small
Published in Nature Communications (2019-11-01)

Genetic interactions affecting human gene expression identified by variance association mapping

by Andrew Anand Brown, Alfonso Buil, Ana Viñuela, Tuuli Lappalainen, Hou-Feng Zheng, J Brent Richards, Kerrin S Small, Timothy D Spector, Emmanouil T Dermitzakis, Richard Durbin
Published in eLife (2014-04-01)

Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort

by Yong Li, Xinyu Yan, Yifan Xu, Robert Pope, Tim D Spector, Mario Falchi, Claire J Steves, Jordana T Bell, Kerrin S Small, Cristina Menni, Rachel Gibson, Ana Rodriguez-Mateos
Published in BMC Medicine (2025-11-01)

Analysis of subcellular RNA fractions demonstrates significant genetic regulation of gene expression in human brain post-transcriptionally

by Karishma D’Sa, Sebastian Guelfi, Jana Vandrovcova, Regina H. Reynolds, David Zhang, John Hardy, Juan A. Botía, Michael E. Weale, Sarah A. Gagliano Taliun, Kerrin S. Small, Mina Ryten
Published in Scientific Reports (2023-08-01)

Epigenetic findings in periodontitis in UK twins: a cross-sectional study

by Yuko Kurushima, Pei-Chien Tsai, Juan Castillo-Fernandez, Alexessander Couto Alves, Julia Sarah El-Sayed Moustafa, Caroline Le Roy, Tim D. Spector, Mark Ide, Francis J. Hughes, Kerrin S. Small, Claire J. Steves, Jordana T. Bell
Published in Clinical Epigenetics (2019-02-01)

Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice

by Satish Patel, Afreen Haider, Anna Alvarez-Guaita, Guillaume Bidault, Julia Sarah El-Sayed Moustafa, Esther Guiu-Jurado, John A. Tadross, James Warner, James Harrison, Samuel Virtue, Fabio Scurria, Ilona Zvetkova, Matthias Blüher, Kerrin S. Small, Stephen O’Rahilly, David B. Savage
Published in Molecular Metabolism (2022-11-01)

Age acquired skewed X chromosome inactivation is associated with adverse health outcomes in humans

by Amy L Roberts, Alessandro Morea, Ariella Amar, Antonino Zito, Julia S El-Sayed Moustafa, Max Tomlinson, Ruth CE Bowyer, Xinyuan Zhang, Colette Christiansen, Ricardo Costeira, Claire J Steves, Massimo Mangino, Jordana T Bell, Chloe CY Wong, Timothy J Vyse, Kerrin S Small
Published in eLife (2022-11-01)

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue.

by Alexander W Drong, George Nicholson, Asa K Hedman, Eshwar Meduri, Elin Grundberg, Kerrin S Small, So-Youn Shin, Jordana T Bell, Fredrik Karpe, Nicole Soranzo, Tim D Spector, Mark I McCarthy, Panos Deloukas, Mattias Rantalainen, Cecilia M Lindgren, MolPAGE Consortia
Published in PLoS ONE (2013-01-01)

RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro

by Nellie Y. Loh, James E. N. Minchin, Katherine E. Pinnick, Manu Verma, Marijana Todorčević, Nathan Denton, Julia El-Sayed Moustafa, John P. Kemp, Celia L. Gregson, David M. Evans, Matt J. Neville, Kerrin S. Small, Mark I. McCarthy, Anubha Mahajan, John F. Rawls, Fredrik Karpe, Constantinos Christodoulides
Published in Nature Communications (2020-06-01)

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Published in Nature Communications (2018-04-01)

Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers

by Colette Christiansen, Max Tomlinson, Melissa Eliot, Emma Nilsson, Ricardo Costeira, Yujing Xia, Sergio Villicaña, Olatz Mompeo, Philippa Wells, Juan Castillo-Fernandez, Louis Potier, Marie-Claude Vohl, Andre Tchernof, Julia El-Sayed Moustafa, Cristina Menni, Claire J. Steves, Karl Kelsey, Charlotte Ling, Elin Grundberg, Kerrin S. Small, Jordana T. Bell
Published in Genome Medicine (2022-07-01)

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS

by David Z. Pan, Kristina M. Garske, Marcus Alvarez, Yash V. Bhagat, James Boocock, Elina Nikkola, Zong Miao, Chelsea K. Raulerson, Rita M. Cantor, Mete Civelek, Craig A. Glastonbury, Kerrin S. Small, Michael Boehnke, Aldons J. Lusis, Janet S. Sinsheimer, Karen L. Mohlke, Markku Laakso, Päivi Pajukanta, Arthur Ko
Published in Nature Communications (2018-08-01)

Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus

by Christopher A. Odhams, Amy L. Roberts, Susan K. Vester, Carolina S. T. Duarte, Charlie T. Beales, Alexander J. Clarke, Sonja Lindinger, Samuel J. Daffern, Antonino Zito, Lingyan Chen, Leonardo L. Jones, Lora Boteva, David L. Morris, Kerrin S. Small, Michelle M. A. Fernando, Deborah S. Cunninghame Graham, Timothy J. Vyse
Published in Nature Communications (2019-05-01)

Smoking induces coordinated DNA methylation and gene expression changes in adipose tissue with consequences for metabolic health

by Pei-Chien Tsai, Craig A. Glastonbury, Melissa N. Eliot, Sailalitha Bollepalli, Idil Yet, Juan E. Castillo-Fernandez, Elena Carnero-Montoro, Thomas Hardiman, Tiphaine C. Martin, Alice Vickers, Massimo Mangino, Kirsten Ward, Kirsi H. Pietiläinen, Panos Deloukas, Tim D. Spector, Ana Viñuela, Eric B. Loucks, Miina Ollikainen, Karl T. Kelsey, Kerrin S. Small, Jordana T. Bell
Published in Clinical Epigenetics (2018-10-01)

Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information

by Sebastian Guelfi, Karishma D’Sa, Juan A. Botía, Jana Vandrovcova, Regina H. Reynolds, David Zhang, Daniah Trabzuni, Leonardo Collado-Torres, Andrew Thomason, Pedro Quijada Leyton, Sarah A. Gagliano Taliun, Mike A. Nalls, International Parkinson’s Disease Genomics Consortium (IPDGC), UK Brain Expression Consortium (UKBEC), Kerrin S. Small, Colin Smith, Adaikalavan Ramasamy, John Hardy, Michael E. Weale, Mina Ryten
Published in Nature Communications (2020-02-01)