Bibliotecas PUC-SP - Busca Integrada

Metastatic penile carcinoma associated with convergent gain-of-function mutations in NOTCH1

Por Sabina Signoretti, Jon C. Aster
Publicado no Human Pathology: Case Reports (2018-03-01)

Mitochondrial transporter expression patterns distinguish tumor from normal tissue and identify cancer subtypes with different survival and metabolism

Por Hartmut Wohlrab, Sabina Signoretti, Lucia E. Rameh, Derrick K. DeConti, Steen H. Hansen
Publicado no Scientific Reports (2022-10-01)

Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate.

Por Jean-Christophe Pignon, Chiara Grisanzio, Ingrid Carvo, Lillian Werner, Meredith Regan, E Lynette Wilson, Sabina Signoretti
Publicado no PLoS ONE (2015-01-01)

p63 promotes cell survival through fatty acid synthase.

Por Venkata Sabbisetti, Arianna Di Napoli, Apryle Seeley, Angela M Amato, Esther O'Regan, Musie Ghebremichael, Massimo Loda, Sabina Signoretti
Publicado no PLoS ONE (2009-06-01)

A Non-integrating Lentiviral Approach Overcomes Cas9-Induced Immune Rejection to Establish an Immunocompetent Metastatic Renal Cancer Model

Por Junhui Hu, Shiruyeh Schokrpur, Maani Archang, Kip Hermann, Allison C. Sharrow, Prateek Khanna, Jesse Novak, Sabina Signoretti, Rupal S. Bhatt, Beatrice S. Knudsen, Hua Xu, Lily Wu
Publicado no Molecular Therapy: Methods & Clinical Development (2018-06-01)

A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

Por Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg, Massimo Loda
Publicado no EMBO Molecular Medicine (2014-10-01)

Regulation of HHLA2 expression in kidney cancer and myeloid cells

Por Tomonari Shigemura, Nahuel Perrot, Zimo Huang, Rupal S. Bhatt, Aseman Bagheri Sheshdeh, Nourhan El Ahmar, Fatme Ghandour, Sabina Signoretti, David F. McDermott, Gordon J. Freeman, Kathleen M. Mahoney
Publicado no BMC Cancer (2023-10-01)

A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis

Por Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg, Massimo Loda
Publicado no EMBO Molecular Medicine (2014-02-01)

Correction to: Outcomes based on plasma biomarkers in METEOR, a randomized phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma

Por Thomas Powles, Toni K. Choueiri, Robert J. Motzer, Eric Jonasch, Sumanta Pal, Nizar M. Tannir, Sabina Signoretti, Rajesh Kaldate, Christian Scheffold, Evelyn Wang, Dana T. Aftab, Bernard Escudier, Daniel J. George
Publicado no BMC Cancer (2021-09-01)

Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma.

Por Lana Hamieh, Toni K Choueiri, Barbara Ogórek, Damir Khabibullin, Daniel Rosebrock, Dimitri Livitz, Andre Fay, Jean-Christophe Pignon, David F McDermott, Neeraj Agarwal, Wenhua Gao, Sabina Signoretti, David J Kwiatkowski
Publicado no PLoS Genetics (2018-09-01)

Outcomes based on plasma biomarkers in METEOR, a randomized phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma

Por Thomas Powles, Toni K. Choueiri, Robert J. Motzer, Eric Jonasch, Sumanta Pal, Nizar M. Tannir, Sabina Signoretti, Rajesh Kaldate, Christian Scheffold, Evelyn Wang, Dana T. Aftab, Bernard Escudier, Daniel J. George
Publicado no BMC Cancer (2021-08-01)

Long-term outcomes with nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma

Por Chung-Wei Lee, Thomas Powles, Sabina Signoretti, Sumanta K Pal, Toni K Choueiri, Brian I Rini, Saby George, Robert J Motzer, Frede Donskov, Scott S Tykodi, Nizar M Tannir, Saurabh Gupta, Ruiyun Jiang
Publicado no Journal for ImmunoTherapy of Cancer (2022-12-01)

Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression.

Por Liang Zhang, Manoj Bhasin, Rachel Schor-Bardach, Xiaoen Wang, Michael P Collins, David Panka, Prabhakar Putheti, Sabina Signoretti, David C Alsop, Towia Libermann, Michael B Atkins, James W Mier, S Nahum Goldberg, Rupal S Bhatt
Publicado no PLoS ONE (2011-04-01)

Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases

Por Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi
Publicado no Journal for ImmunoTherapy of Cancer (2023-08-01)

1017 SLAMF7+ CD8+ exhausted T cell-specific gene signature is associated with resistance to PD1 blockade in renal cell carcinoma

Por Michael Hurwitz, Elizabeth Plimack, Jeffrey Sosman, Sabina Signoretti, David F McDermott, Michael B Atkins, Naomi B Haas, Hans Hammers, Nicholas Schindler, Opeyemi A Jegede, Catherine J Wu, David Braun, Miya Hugaboom, Kelly Street, Neil Ruthen, Lena Wirth
Publicado no Journal for ImmunoTherapy of Cancer (2023-11-01)

Anti-CAIX BBζ CAR4/8 T cells exhibit superior efficacy in a ccRCC mouse model

Por Yufei Wang, Alicia Buck, Marion Grimaud, Aedin C. Culhane, Sreekumar Kodangattil, Cecile Razimbaud, Dennis M. Bonal, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Madison L. O'Donnell, Ying Huang, Sabina Signoretti, Toni K. Choueiri, Gordon J. Freeman, Quan Zhu, Wayne A. Marasco
Publicado no Molecular Therapy: Oncolytics (2022-03-01)

442 CAIX targeted CAR-T cells exhibited antitumor efficacy on renal cell carcinoma (RCC) patient derived organotypic tumor spheroids (PDOTS)

Por Sabina Signoretti, Toni K Choueiri, Cloud Paweletz, Kun Huang, Yufei Wang, Gordon Freeman, Alicia Buck, Gabriella Kastrunes, Marion Grimaud, Atef Fayed, Luann Zerefa, Brandon Piel, Elena Ivanova, Miriam Ficial, Jon Wee, David Barbie, Wayne Marasco, Andras-Gabor Miklosi, Tran Thai, Ming-Ru Wu
Publicado no Journal for ImmunoTherapy of Cancer (2023-11-01)

Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1

Por Hsiao-Yun Chen, Yavuz T. Durmaz, Yixiang Li, Amin H. Sabet, Amir Vajdi, Thomas Denize, Emily Walton, Yasmin Nabil Laimon, John G. Doench, Navin R. Mahadevan, Julie-Aurore Losman, David A. Barbie, Michael Y. Tolstorukov, Charles M. Rudin, Triparna Sen, Sabina Signoretti, Matthew G. Oser
Publicado no Nature Communications (2022-08-01)

Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.

Por Krinio Giannikou, Izabela A Malinowska, Trevor J Pugh, Rachel Yan, Yuen-Yi Tseng, Coyin Oh, Jaegil Kim, Magdalena E Tyburczy, Yvonne Chekaluk, Yang Liu, Nicola Alesi, Geraldine A Finlay, Chin-Lee Wu, Sabina Signoretti, Matthew Meyerson, Gad Getz, Jesse S Boehm, Elizabeth P Henske, David J Kwiatkowski
Publicado no PLoS Genetics (2016-08-01)

Identification of ALK gene alterations in urothelial carcinoma.

Por Joaquim Bellmunt, Shamini Selvarajah, Scott Rodig, Marta Salido, Silvia de Muga, Irmgard Costa, Beatriz Bellosillo, Lillian Werner, Stephanie Mullane, André P Fay, Robert O'Brien, Jordi Barretina, André E Minoche, Sabina Signoretti, Clara Montagut, Heinz Himmelbauer, David M Berman, Philip Kantoff, Toni K Choueiri, Jonathan E Rosenberg
Publicado no PLoS ONE (2014-01-01)