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Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.

Mitochondrial dysfunction has been observed in skeletal muscle of people with diabetes and insulin-resistant individuals. Furthermore, inherited mutations in mitochondrial DNA can cause a rare form of diabetes. However, it is unclear whether mitochondrial dysfunction is a primary cause of the common...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Genetics
Päätekijät: Ayellet V Segrè, DIAGRAM Consortium, MAGIC investigators, Leif Groop, Vamsi K Mootha, Mark J Daly, David Altshuler
Aineistotyyppi: Artikkeli
Julkaistu: Public Library of Science (PLoS) 2010-08-01
Linkit:http://europepmc.org/articles/PMC2920848?pdf=render
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