Bibliotecas PUC-SP - Busca Integrada

Developing a gene model for simulations that incorporates multi-species conservation

per David Altshuler.
Publicat 2014

Proxy genotypes and phenotypes for human genetics

per David Altshuler and Mark Daly.
Publicat 2009

Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.

per Ayellet V Segrè, DIAGRAM Consortium, MAGIC investigators, Leif Groop, Vamsi K Mootha, Mark J Daly, David Altshuler
Publicat a PLoS Genetics (2010-08-01)

Efficiency and power as a function of sequence coverage, SNP array density, and imputation.

per Jason Flannick, Joshua M Korn, Pierre Fontanillas, George B Grant, Eric Banks, Mark A Depristo, David Altshuler
Publicat a PLoS Computational Biology (2012-01-01)

Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function.

per Soumya Raychaudhuri, Joshua M Korn, Steven A McCarroll, International Schizophrenia Consortium, David Altshuler, Pamela Sklar, Shaun Purcell, Mark J Daly
Publicat a PLoS Genetics (2010-09-01)

Testing for an unusual distribution of rare variants.

per Benjamin M Neale, Manuel A Rivas, Benjamin F Voight, David Altshuler, Bernie Devlin, Marju Orho-Melander, Sekar Kathiresan, Shaun M Purcell, Kathryn Roeder, Mark J Daly
Publicat a PLoS Genetics (2011-03-01)

Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

per Soumya Raychaudhuri, Robert M Plenge, Elizabeth J Rossin, Aylwin C Y Ng, International Schizophrenia Consortium, Shaun M Purcell, Pamela Sklar, Edward M Scolnick, Ramnik J Xavier, David Altshuler, Mark J Daly
Publicat a PLoS Genetics (2009-06-01)

Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups.

per Kevin M Waters, Daniel O Stram, Mohamed T Hassanein, Loïc Le Marchand, Lynne R Wilkens, Gertraud Maskarinec, Kristine R Monroe, Laurence N Kolonel, David Altshuler, Brian E Henderson, Christopher A Haiman
Publicat a PLoS Genetics (2010-08-01)

The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease.

per Loukas Moutsianas, Vineeta Agarwala, Christian Fuchsberger, Jason Flannick, Manuel A Rivas, Kyle J Gaulton, Patrick K Albers, GoT2D Consortium, Gil McVean, Michael Boehnke, David Altshuler, Mark I McCarthy
Publicat a PLoS Genetics (2015-04-01)

The case for selection at CCR5-Delta32.

per Pardis C Sabeti, Emily Walsh, Steve F Schaffner, Patrick Varilly, Ben Fry, Holli B Hutcheson, Mike Cullen, Tarjei S Mikkelsen, Jessica Roy, Nick Patterson, Richard Cooper, David Reich, David Altshuler, Stephen O'Brien, Eric S Lander
Publicat a PLoS Biology (2005-11-01)

Correction: African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts.

per Ching-Yu Cheng, David Reich, Christopher A. Haiman, Arti Tandon, Nick Patterson, Selvin Elizabeth, Ermeg L. Akylbekova, Frederick L. Brancati, Josef Coresh, Eric Boerwinkle, David Altshuler, Herman A. Taylor, Brian E. Henderson, James G. Wilson, W. H. Linda Kao
Publicat a PLoS ONE (2012-01-01)

African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts.

per Ching-Yu Cheng, David Reich, Christopher A Haiman, Arti Tandon, Nick Patterson, Elizabeth Selvin, Ermeg L Akylbekova, Frederick L Brancati, Josef Coresh, Eric Boerwinkle, David Altshuler, Herman A Taylor, Brian E Henderson, James G Wilson, W H Linda Kao
Publicat a PLoS ONE (2012-01-01)

Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.

per Edwin Choy, Roman Yelensky, Sasha Bonakdar, Robert M Plenge, Richa Saxena, Philip L De Jager, Stanley Y Shaw, Cara S Wolfish, Jacqueline M Slavik, Chris Cotsapas, Manuel Rivas, Emmanouil T Dermitzakis, Ellen Cahir-McFarland, Elliott Kieff, David Hafler, Mark J Daly, David Altshuler
Publicat a PLoS Genetics (2008-11-01)

Genetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.

per Toni I Pollin, Tamara Isakova, Kathleen A Jablonski, Paul I W de Bakker, Andrew Taylor, Jarred McAteer, Qing Pan, Edward S Horton, Linda M Delahanty, David Altshuler, Alan R Shuldiner, Ronald B Goldberg, Jose C Florez, Paul W Franks, Diabetes Prevention Program Research Group
Publicat a PLoS Genetics (2012-01-01)

TXNIP regulates peripheral glucose metabolism in humans.

per Hemang Parikh, Emma Carlsson, William A Chutkow, Lovisa E Johansson, Heidi Storgaard, Pernille Poulsen, Richa Saxena, Christine Ladd, P Christian Schulze, Michael J Mazzini, Christine Bjørn Jensen, Anna Krook, Marie Björnholm, Hans Tornqvist, Juleen R Zierath, Martin Ridderstråle, David Altshuler, Richard T Lee, Allan Vaag, Leif C Groop, Vamsi K Mootha
Publicat a PLoS Medicine (2007-05-01)

Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.

per Gavin Lucas, Carla Lluís-Ganella, Isaac Subirana, Muntaser D Musameh, Juan Ramon Gonzalez, Christopher P Nelson, Mariano Sentí, Myocardial Infarction Genetics Consortium, Wellcome Trust Case Control Consortium, Stephen M Schwartz, David Siscovick, Christopher J O'Donnell, Olle Melander, Veikko Salomaa, Shaun Purcell, David Altshuler, Nilesh J Samani, Sekar Kathiresan, Roberto Elosua
Publicat a PLoS ONE (2012-01-01)

Genetic variation in the HSD17B1 gene and risk of prostate cancer.

per Peter Kraft, Paul Pharoah, Stephen J Chanock, Demetrius Albanes, Laurence N Kolonel, Richard B Hayes, David Altshuler, Gerald Andriole, Christine Berg, Heiner Boeing, Noel P Burtt, Bas Bueno-de-Mesquita, Eugenia E Calle, Howard Cann, Federico Canzian, Yen-Ching Chen, David E Crawford, Alison M Dunning, Heather S Feigelson, Matthew L Freedman, John M Gaziano, Ed Giovannucci, Carlos Alberto Gonzalez, Christopher A Haiman, Goran Hallmans, Brian E Henderson, Joel N Hirschhorn, David J Hunter, Rudolf Kaaks, Timothy Key, Loic Le Marchand, Jing Ma, Kim Overvad, Domenico Palli, Malcolm C Pike, Elio Riboli, Carmen Rodriguez, Wendy V Setiawan, Meir J Stampfer, Daniel O Stram, Gilles Thomas, Michael J Thun, Ruth Travis, Antonia Trichopoulou, Jarmo Virtamo, Sholom Wacholder
Publicat a PLoS Genetics (2005-11-01)

Informed conditioning on clinical covariates increases power in case-control association studies.

per Noah Zaitlen, Sara Lindström, Bogdan Pasaniuc, Marilyn Cornelis, Giulio Genovese, Samuela Pollack, Anne Barton, Heike Bickeböller, Donald W Bowden, Steve Eyre, Barry I Freedman, David J Friedman, John K Field, Leif Groop, Aage Haugen, Joachim Heinrich, Brian E Henderson, Pamela J Hicks, Lynne J Hocking, Laurence N Kolonel, Maria Teresa Landi, Carl D Langefeld, Loic Le Marchand, Michael Meister, Ann W Morgan, Olaide Y Raji, Angela Risch, Albert Rosenberger, David Scherf, Sophia Steer, Martin Walshaw, Kevin M Waters, Anthony G Wilson, Paul Wordsworth, Shanbeh Zienolddiny, Eric Tchetgen Tchetgen, Christopher Haiman, David J Hunter, Robert M Plenge, Jane Worthington, David C Christiani, Debra A Schaumberg, Daniel I Chasman, David Altshuler, Benjamin Voight, Peter Kraft, Nick Patterson, Alkes L Price
Publicat a PLoS Genetics (2012-01-01)

Correction: The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits.

per Benjamin F. Voight, Hyun Min Kang, Jun Ding, Cameron D. Palmer, Carlo Sidore, Peter S. Chines, Noël P. Burtt, Christian Fuchsberger, Yanming Li, Jeanette Erdmann, Timothy M. Frayling, Iris M. Heid, Anne U. Jackson, Toby Johnson, Tuomas O. Kilpeläinen, Cecilia M. Lindgren, Andrew P. Morris, Inga Prokopenko, Joshua C. Randall, Richa Saxena, Nicole Soranzo, Elizabeth K. Speliotes, Tanya M. Teslovich, Eleanor Wheeler, Jared Maguire, Melissa Parkin, Simon Potter, N. William Rayner, Neil Robertson, Kathleen Stirrups, Wendy Winckler, Serena Sanna, Antonella Mulas, Ramaiah Nagaraja, Francesco Cucca, Inês Barroso, Panos Deloukas, Ruth J. F. Loos, Sekar Kathiresan, Patricia B. Munroe, Christopher Newton-Cheh, Arne Pfeufer, Nilesh J. Samani, Heribert Schunkert, Joel N. Hirschhorn, David Altshuler, Mark I. McCarthy, Gonçalo R. Abecasis, Michael Boehnke
Publicat a PLoS Genetics (2013-04-01)

The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits.

per Benjamin F Voight, Hyun Min Kang, Jun Ding, Cameron D Palmer, Carlo Sidore, Peter S Chines, Noël P Burtt, Christian Fuchsberger, Yanming Li, Jeanette Erdmann, Timothy M Frayling, Iris M Heid, Anne U Jackson, Toby Johnson, Tuomas O Kilpeläinen, Cecilia M Lindgren, Andrew P Morris, Inga Prokopenko, Joshua C Randall, Richa Saxena, Nicole Soranzo, Elizabeth K Speliotes, Tanya M Teslovich, Eleanor Wheeler, Jared Maguire, Melissa Parkin, Simon Potter, N William Rayner, Neil Robertson, Kathleen Stirrups, Wendy Winckler, Serena Sanna, Antonella Mulas, Ramaiah Nagaraja, Francesco Cucca, Inês Barroso, Panos Deloukas, Ruth J F Loos, Sekar Kathiresan, Patricia B Munroe, Christopher Newton-Cheh, Arne Pfeufer, Nilesh J Samani, Heribert Schunkert, Joel N Hirschhorn, David Altshuler, Mark I McCarthy, Gonçalo R Abecasis, Michael Boehnke
Publicat a PLoS Genetics (2012-01-01)